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| The New Economics of Biologics: Breaking the $50/g Barrier | What do different processing scenarios mean for mAb manufacturing economics? In this new report, cost modeling shows that intensified single-use and continuous processes can reduce costs across demand levels, while stainless-steel facilities become cost-competitive only at higher titers and larger campaign sizes. Read the report to explore the economics of breaking the $50/g barrier. |
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By Jose Saiz de Omeñaca | Nearly all the industry's emissions happen upstream from core manufacturing functions. This puts sustainability almost entirely on the shoulders of purchasing. | |
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FOCUS ON PROCESS ENGINEERING |
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| Transitioning mRNA Production To cGMP Requires Early Engagement | White Paper | By Telmo Graça, Ph.D. and Ilaria Pettinati, Ph.D., Lonza | Early choices in capping strategy, IVT conditions, raw materials, and downstream design shape yield, cost, and quality in mRNA manufacturing, and can determine whether a cGMP campaign succeeds. |
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| Using Digital Tools In Process Development | Poster | By Dr. Alexander Krauland and Hermann Schuchnigg, Boehringer Ingelheim Biopharmaceuticals GmbH | Technology can transform the entire biopharma production process chain. Using integrated process models, machine learning, and genetic algorithms has made production faster and more efficient. |
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| Innovations In Peptide Manufacturing | Article | Federal Equipment Company | The peptide manufacturing industry is evolving to meet the demands of efficiency, scalability, and sustainability. Learn how the latest innovations are addressing these challenges. |
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| Rethinking Capital Efficiency In Cell Processing | Article | CARR Biosystems | In cell processing, rigid, single-function equipment can lead to inefficiencies, wasted space, and scheduling conflicts. A versatile approach can help teams do more with less. |
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| Strategies To Accelerate Gene Therapy Process Development | Poster | By Dogan Ornek, XingchengChen, Hassan Sakhtah, et al., Boston Institute of Biotechnology (BIB) | Gene therapy developers are accelerating timelines with platform approaches, DoE, stronger development-manufacturing alignment, and PAT tools to reach late-phase manufacturing faster. |
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| Overview Of Recombinant Protein Expression Systems | Article | Contributors: Ela Dudek Ph.D., Paige Grant M.S.c, Diane Jeon B.Com, Anzer Khan Ph.D., Laine Lysyk M.S.c, Tautvydas Paskevicius Ph.D., Simon Wu M.S.c, Future Fields | Compare leading protein expression platforms and see how complexity, scalability, cost, and quality shape the path to commercial production. |
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| Coordinated Drug Development As An Execution Framework | White Paper | Thermo Fisher Scientific | When research, manufacturing, and supply operate in silos, every phase transition resets alignment. Here, the authors observe what changes when those functions operate within a shared framework. |
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| Understanding Magnetic Tweezers Use In Single Molecule Microscopy | Article | By Jenice Con Foo, Ph.D., Mad City Labs, Inc. | Magnetic tweezer experiments often seek to measure changes in the extension or relaxation of a polymer, a functionality useful, for example, in exploring how different enzymes manipulate polymer structures. |
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PROCESS ENGINEERING SOLUTIONS |
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