Newsletter | November 6, 2026

11.06.26 -- Building Sustainable Biopharma Supply Chains Starts With Procurement

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The New Economics of Biologics: Breaking the $50/g Barrier

What do different processing scenarios mean for mAb manufacturing economics? In this new report, cost modeling shows that intensified single-use and continuous processes can reduce costs across demand levels, while stainless-steel facilities become cost-competitive only at higher titers and larger campaign sizes. Read the report to explore the economics of breaking the $50/g barrier.

FOCUS ON SUPPLY CHAIN

Building Sustainable Biopharma Supply Chains Starts With Procurement

Nearly all the industry's emissions happen upstream from core manufacturing functions. This puts sustainability almost entirely on the shoulders of purchasing.

A Comparative Analysis Between Liquid Nitrogen And Mechanical Freezers

Explore the differences between liquid nitrogen and mechanical cryogenic freezers, as well as how each method supports scientific, medical, and industrial storage needs.

PTFE Containment: Viable For Temperature-Sensitive Protection

See why single-use cold-chain containers made with polytetrafluoroethylene fluoropolymers may be less susceptible to failure and breakage at cold temperatures.

Product Carbon Footprint: Enabling Product-Level Decarbonization

Facility-level and spend-based carbon accounting leave critical gaps in biopharma Scope 3 management. Examine how batch-level product carbon footprinting changes what's measurable and what's actionable.

SUPPLY CHAIN SOLUTIONS

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Protective Shell For 2D Bags: Engineered For Mechanical Protection - Repligen

FOCUS ON PROCESS ENGINEERING

Transitioning mRNA Production To cGMP Requires Early Engagement

Early choices in capping strategy, IVT conditions, raw materials, and downstream design shape yield, cost, and quality in mRNA manufacturing, and can determine whether a cGMP campaign succeeds.

Evaluation Of Process Indicators For Hydrogen Peroxide Decontamination

Immediate, quantifiable verification replaces seven-day incubation periods. Discover how enzyme-based indicators optimize hydrogen peroxide decontamination.

Using Digital Tools In Process Development

Technology can transform the entire biopharma production process chain. Using integrated process models, machine learning, and genetic algorithms has made production faster and more efficient.

Innovations In Peptide Manufacturing

The peptide manufacturing industry is evolving to meet the demands of efficiency, scalability, and sustainability. Learn how the latest innovations are addressing these challenges.

Rethinking Capital Efficiency In Cell Processing

In cell processing, rigid, single-function equipment can lead to inefficiencies, wasted space, and scheduling conflicts. A versatile approach can help teams do more with less.

Real-Time Viable Particle Detection For Definitive Root Cause Investigation

Investigations into viable air excursions are difficult to perform using traditional methods. Uncover why a real-time viable particle counter is key to providing process improvement.

Strategies To Accelerate Gene Therapy Process Development

Gene therapy developers are accelerating timelines with platform approaches, DoE, stronger development-manufacturing alignment, and PAT tools to reach late-phase manufacturing faster.

Discover Accelerated Approaches For Successful Commercial Filing

Early risk assessment, leaner scale-down model qualification, and tighter process characterization scope offer the clearest time savings in microbial filings, each with scientific trade-offs worth weighing.

Overview Of Recombinant Protein Expression Systems

Compare leading protein expression platforms and see how complexity, scalability, cost, and quality shape the path to commercial production.

Coordinated Drug Development As An Execution Framework

When research, manufacturing, and supply operate in silos, every phase transition resets alignment. Here, the authors observe what changes when those functions operate within a shared framework.

Where The Future Is Now In Life Sciences And BioPharma

Middlesex County, NJ, is a premier life sciences hub, attracting major biopharma leaders, entrepreneurs, and investors to accelerate global medical innovation.

Streamline Your Pathway To IND With A Rapid Tox Approach

With tox material in hand as soon as possible, antibody-derived drug developers can conduct their tox studies earlier, facilitating a timely IND submission and speeding up pathways to patients.

Achieving Cell Therapy Success: Reducing Costs To Improve Patient Access

To ensure the commercial success of cell therapies, developers must adopt innovative manufacturing and QC technologies that reduce COGS while enhancing scalability, quality, and clinical outcomes.

From 2D To Organ-On-A-Chip: Platforms Powering Modern Disease Models

Disease modeling has evolved well beyond animal studies, and understanding which platform fits which research question is now a critical skill for modern biology teams.

A Unified Development Blueprint For Accelerating Timelines

Find out how early integration of cell line engineering, process development, and analytics compressed a complex antibody program from DNA to drug substance bulk fill in just 8.5 months.

Co-Precipitation Of Metal Carbonate Templated Protein Microparticles

Delve into the automated production of protein microparticles using an innovative method that offers a standardized and scalable solution for co-precipitation in biopolymer particle fabrication.

Optimizing Upstream High-Throughput Biologics Development

Gain insight into designing large Design-of-Experiment (DOE) upstream process development studies and the elements that could positively or negatively effect your throughput.

Understanding Magnetic Tweezers Use In Single Molecule Microscopy

Magnetic tweezer experiments often seek to measure changes in the extension or relaxation of a polymer, a functionality useful, for example, in exploring how different enzymes manipulate polymer structures. 
 
  

PROCESS ENGINEERING SOLUTIONS

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Building The Infrastructure Behind Cell Therapy Manufacturing - CellBri

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How Can We Help You Achieve Drug Product Risk Control? - Cytiva

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Risk Tool Selector: Match The Framework To The Decision - ValGenesis

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Pharmaceutical Operational Readiness Programs - CAI

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