Newsletter | December 5, 2025

12.05.25 -- ADCs: Advancements And Insights

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Live Event: How Digital Tools Are Accelerating Biopharma Development

Register today for this digital event led by Bioprocess Online’s chief editor, Tyler Menichiello, features industry experts who will share for an engaging panel discussion on how companies are deploying advanced technologies and tools to accelerate biopharmaceutical development. This event is free to attend thanks to Cytiva.

FOCUS ON PROCESS ENGINEERING

ADCs: Advancements And Insights

Discover how innovative assays, linker technologies, advanced containment strategies, and robotic automation are addressing ADC development challenges—from internalization and stability to safety and manufacturing efficiency.

How To Develop Reliable, Repeatable Microbial Processes At Any Scale

Developing robust, scalable microbial fermentation depends on optimizing growth and expression phases through efficient oxygen transfer, fine-tuning of nutrient delivery, and induction of protein expression.

Fluorescent Western Blot Detection

Review this step-by-step guidance for fluorescent western blot detection, including membrane prep and antibody handling, to improve signal clarity and consistency across imaging platforms.

CMC Development Bottlenecks: The True Impact Of Manual Processes

Manual processes in CMC development create costly delays and compliance risks. Learn how digitization can eliminate bottlenecks, improve traceability, and accelerate timelines.

Viral Gene Therapy: Reducing Costs To Improve Patient Access

Gene therapy is revolutionizing medicine with its potential to cure genetic disorders. As approvals rise, so do concerns about accessibility, with million-dollar price tags limiting patient access.

Linking mAb Product Quality Profile Changes To Your BioProcess

Optimize your bioprocess and product quality with high-frequency data. Discover how to streamline mAb characterization and link process changes to product attributes.

Driving Efficiency Through Process Intensification

Discover how intensification strategies reduce costs and waste while boosting throughput, sustainability, and operational value, which offers a smarter, more scalable approach to manufacturing.

Automating The Process Of Filling Media Into Bottles

Learn how a vaccine manufacturer using a wide range of containers for media and buffer filling was able to increase efficiency by 70% with an automated closed-system solution.

The Absolute Essentials Of Manufacturability

Learn why integrating Quality by Design (QbD) and Process Analytical Technology (PAT) early on is essential for developing a robust, controlled, and financially viable process.

mRNA Vaccines And Therapeutics: Current Trends And Perspectives

Delve into the advancements and transformative impact of mRNA vaccine technology on modern medicine and explore how this technology is revolutionizing healthcare for the future and beyond.

Immunogenicity — Challenge For Protein Drugs

This presentation discusses the shift in pharmaceuticals from small-molecule drugs to protein biologics and the associated challenges, particularly the immunogenic response.

Next Gen Plasmid Technology: Improve Performance, Safety, Manufacturing

Nanoplasmids have paved the way for facilitating a wide range of cell and gene therapeutic applications. Gain an overview of a novel technology and specific benefits.

Accelerating mRNA Therapy Production With Digital Innovation

Scaling mRNA therapies requires more than innovation—it demands precision. Discover how digital tools like automation and analytics are helping life science companies streamline production.

Enabling Accelerated Raman Model Calibration For Real-Time Monitoring

Raman spectroscopy is a key component of a PAT strategy. Evaluate an innovative workflow designed to streamline the integration of an in-line Raman analyzer for bioreactor applications.

PROCESS ENGINEERING SOLUTIONS

The Digital Suite For Process Lifecycle Intelligence - ValGenesis

It's Time To Intensify - Sartorius

FOCUS ON SUPPLY CHAIN

Trends In Cold Chain Storage For Biologics

Packaging is critical, as biotechnology products requiring colder storage become more valuable. Find out how you can improve your temperature-controlled supply chain and meet cold chain storage demands.

Understanding Refrigerator, Freezer, And Incubator Performance Metrics

Learn more about how refrigerators, freezers, and incubators are vital to scientific progress to preserve samples, support experiments, and ensure the integrity of life-saving research in every modern laboratory.

A Step-By-Step Guide To Cell Banking

Cell banking stands at the forefront of medical advancement. This guide delves into the steps involved in protecting these priceless resources, from cell collection and processing to storage and cell expansion.

Friendshoring: A Strategic Shift In Pharma Supply Chains

To safeguard the consistent delivery of essential therapies to patients around the world, biopharmaceutical companies, alongside their CDMO partners, are rethinking traditional supply models.

SUPPLY CHAIN SOLUTIONS

World Grade Solvents: Multi-Compendial Products for Global Markets - Greenfield Global

Flexible Freeze Containers For Bulk Drug Storage And Transport - W.L. Gore & Associates

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