UPSTREAM CELL CULTURE AND FERMENTATION
Leveraging Single-Use Bioreactors In Bench-Scale Process Development
Scaling bioprocesses requires matching critical variables to ensure consistent cell behavior and product quality. Optimize operations with efficient tools that enable more experiments per year.
Cell Culture Media Manufacturing, Paisley, Scotland
Learn more about our cell culture media manufacturing global network, including details of the Paisley, Scotland site's capacity expansion supporting the bioprocessing industry's rapidly growing needs.
RNA-LNP Manufacturing Technology Delivering Transformative Medicines
NxGen™ microfluidic technology enables controlled and precise assembly of high-quality, uniform LNPs, ensuring reproducible scale-up of RNA-LNPs while maximizing drug loading and particle quality.
Go Beyond Custom Media Screening And Prototyping
Learn about manufacturing solutions that streamline cell culture media scale-up with global production capabilities, equivalency strategies, and quality assurance for reliable supply.
MES Apps Built For Speed And Seamless Integration
Digitize bioprocess workflows to achieve consistent, paper-free execution that deploys up to 66% quicker than traditional MES with a cloud-based, no-code platform built for single-use bioprocessing.
Five Reasons To Choose Single-Use Bioreactors
Explore five key advantages of single-use bioreactors, including scalable design, homogeneous mixing, broad chemical compatibility, and streamlined seed train processes for bioproduction success.
Enabling Assurance Of Supply Through Evolving Bioprocessing Needs
This featured event at the Gibco cell culture media 60th-anniversary in Grand Island, New York spotlights proactive strategies used by Thermo Fisher Scientific to decrease risk, ensure quality and meet customers raw material needs worldwide.
Perfusion: Medium Selection And Testing
An examination of what to consider in a perfusion medium, including varying reconstituted concentrations, supporting multiple cell clones, allowing for high cell densities at low medium exchange rates, and using it in various types of perfusion.
Discover The Benchtop DynaDrive Single-Use Bioreactor
Ready to transform your process development? Introducing the 5 L Thermo Scientific DynaDrive Single‑Use Bioreactor (S.U.B.), now available! Experience the same bioreactor design from bench to commercial and re‑imagine scalability in process development.
DynaDrive Single-Use Bioreactors Drilled-Hole Sparge Technology
Uniform bubble size and consistent mass transfer across scales through drilled-hole sparge technology improves oxygen delivery and CO2 stripping in demanding cell culture processes.
Cell Insights By Umetrics® Studio
Cell Insights by Umetrics® Studio simplifies advanced data analytics for bioprocessing, offering hybrid modeling, virtual bioreactor simulations, and cell insights to streamline development, and support data-driven decisions.
Nunc Automatic Cell Factory Manipulator Video
Specifically designed to lend innovation and efficiency for highly-effective upstream or downstream applications in large-scale cell culture and production of vaccines, cell therapeutics or other biological products.
DynaDrive S.U.B. Video Series
Explore DynaDrive Single-Use Bioreactors through expert videos covering reactor design, mixing performance, sparge technology, and scalable workflows from bench-scale to commercial production.
Why Is The Bioreactor Square? The Geometry Behind Exceptional Mixing
Cuboid bioreactor design eliminates vortexing through natural baffling, delivering homogeneous mixing and consistent nutrient distribution for high cell density upstream processes.
Demo Of At-Line Cell Culture Media Analyzer
In two minutes, watch how to load a sample and run this powerful analyzer that can provide results on 30+ cell media analytes. Waiting for a report on the core lab can be a thing of the past if you can simply analyze a sample right from your lab bench.
Perfusion: Planning A Run
Learn about a logical approach for defining the operation of a perfusion run. We will break down the process using the three following steps: knowledge space, design space, and control space.
How To Use 5 And 10L BPCs Of The CTS Optmizer Family Of Serum Free Media
Gibco™ CTS™ OpTmizer™ T Cell Expansion SFM, no phenol red, and Gibco™ CTS™ OpTmizer™ Pro SFM are now available in 5 L and 10 L volumes in Thermo Scientific™ BioProcess Containers.
Perfusion: Hardware Needs
In this video, we will discuss cell retention mechanisms, pumps, and intensification challenges in the perfusion process.
Scale With Confidence From Bench To Commercial Production
Consistent vessel design, sparging, and bag materials across 1L to 5,000L volumes enable predictable bioreactor scale-up from development through commercial manufacturing.
Nanoassemblr Blaze mRNA Vaccine Demo
NxGen Technology delivers a scalable means to perform the critical particle formation step in a nanomedicine development process.
Advanced Single-Use Mixing Systems
The Mobius® MIX single-use mixing systems delivers advanced technology to make and purify plasmid DNA and mRNA.
DynaDrive Single-Use Bioreactors - One Reactor, Many Volumes
Single-use bioreactors with turndown ratios up to 20:1 enable facilities to operate across wide volume ranges within the same vessel, streamlining seed trains and reducing capital requirements for multi-product operations.
Bioprocessing Solutions For Cell Culture
Whatever the scope of your project, you can choose from our unmatched portfolio of high-impact produCTS and services to deliver consistent, scalable solutions.
A Next-Level Innovation In Single-Use Bioreactors—Unmatched Design, Scalability, And Performance
Building upon the success of the robust bioreactors first launched in 2006 and updated in 2013, we introduce our newest innovation: the Thermo ScientificTM DynaDrive Single-Use Bioreactor. This single-use bioreactor was designed to accommodate modern cell cultu...
Bioprocessing Equipment And Automation Product Portfolio Overview
Accelerate biotherapeutic development with innovative bioprocessing equipment and automation solutions that feature single-use mixers, bioreactors, and more to streamline workflows and speed products to market.
Accelerating The Development Of New Protein Therapeutics
With Foetal Bovine Serum out of the picture, how do we support cells during cryopreservation and revival to accelerate workflows and reduce costs?
HyPerforma 5:1 Single-Use Bioreactor (S.U.B.) Setup And Installation Part 3
This video is part 3 of 3 videos that cover setup and installation topics related to the HyPerforma 5:1 Single-Use Bioreactor, or S.U.B. In this video we will cover probe assembly, making CPC AseptiQuik connections, probe insertion.
OsmoTECH® HT Automated Micro-Osmometer
The automation-friendly OsmoTECH HT, the only plate-based micro-osmometer, is designed in a 96 well format that ensures efficiency and acceleration of osmolality testing in early upstream process development, formulation development and stability testing.
Introducing The Thermo Scientific™ DynaDrive Single-Use Bioreactor
Explore a single-use bioreactor that has been fully optimized for modern cell culture processes with a cubical vessel design and an innovative, efficient mixing system.
HyPerforma 5:1 Single-Use Bioreactor (S.U.B.) Setup And Installation Part 1
This video is part 1 of 3 videos that cover setup and installation topics related to the HyPerforma 5:1 Single-Use Bioreactor, or S.U.B. In this video we will cover 5:1 system component labeling, preparing the load cells.