FEATURED ARTICLES

• Stainless Steel Vial Filling System Developed For Use In Vaccine Facilities

  TAP Biosystems (now part of the Sartorius Stedim Biotech Group), a leading supplier of innovative cell culture and fermentation systems for life science applications, recently announced the development of a stainless steel version of the fill-it system, designed for safely dispensing biohazardous materials such as vaccine stocks.

• Hamilton Expands The pH Range Of Reversed-Phase Chromatography With Highly Efficient HPLC Column
• Hamilton’s Microlab 300 Redefines Hand-Held Pipetting
• EMD Millipore Launches Mobius CellReady 50 L Single-Use Stirred Tank Bioreactor

WHITE PAPERS & CASE STUDIES

• Process For Scale-Up Of Adherent Vero Cells From Static Cell Factories To Influenza Production

  In cell culture-based vaccine production, scale-up of adherent cells is challenging. This study shows a process for scaling up adherent Vero cells from static cell factories to influenza production at 50 L scale using WAVE Bioreactor™ systems and ReadyToProcess single-use equipment.

• Scale-Up Of Microbial Fermentation Using Recombinant E. Coli

  Fermentation production facilities can utilize the Thermo Scientific™ HyPerforma™ Single-Use Fermentor (S.U.F.) instead of traditional stainless steel cleaning-in-place/ sterilization-in-place (CIP/SIP) fermentor vessels without modifying their existing procedures.

• Challenges And Solutions Of Scalable Cultivation For Anchorage Dependent Cells In Single-Use Bioreactor

  Microcarrier (MC)-based suspension culture processes have been used to culture anchorage-dependent cells in bioreactors. However, scale-up of the process for high cell growth and productivity poses many challenges. By Brian Lee, Yas Hashimura, Daniel Giroux, Marcos Sousa, Joao Clemente, Manuel Carrondo, Siddharth Gupta, Michael McCaman, and Yong-Jae Kim

• Cultivation Of Aggressive Microbial Cultures Of Pichia And Bacillus

  Advances in single-use bioprocess technology have led to the rapid adoption of single-use bioreactors (S.U.B.s) across a broad range of applications within the biotechnology industry.