DOWNSTREAM ISOLATION AND PURIFICATION
Eshmuno® CMX ADC Polishing Animation
This animation demonstrates how Eshmuno® CMX Chromatography Resin removes undesired low DAR and high DAR species, enabling the best pharmacokinetics, efficacy, half-life and tolerability.
Purification Platform For IgMs
Understand the challenges of IgM purification and how to design a scalable non-affinity based purification platform for manufacture of diagnostic IgMs.
Chromatography Resins And Continuous Bioprocessing
In this video Bio-Rad's Process Chromatography Consultant, Jim Sulzberger speaks about continuous bioprocessing and chromatography resins.
Effective Processes For Virus Purification
An informative presentation focused on understanding the challenges in virus/VLP purification, choosing the appropriate (or right) chromatography media for the production virus particles, and developing chromatography methods for optimal binding selectivity and recov...
Single-pass Tangential Flow Filtration For Bioprocessing
Experiencing bottlenecks in your downstream process? Pellicon® Single-Pass TFF increases your productivity, capacity while reducing costs!
Downstream Purification Symposium Overview
A focus on strategies for virus and monoclonal antibody purification, viral clearance, and aggregate removal challenges
Robust Workflow For Single Cell Cloning Of iPSCs For Making cGMP Master Cell Banks
We demonstrate a platform combination of Solentim instrumentation (the VIPS™) and soluble matrix (MatriClone™, based on laminin) for the high-efficiency, high-viability single-cell cloning of iPSCs to form the Master Cell Bank.
Development Of A cGMP-Ready Purification Process, Carsten Voß Video
Purification results are presented of a cGMP-ready process developed for a recombinant adenovirus. The two-step column process results in an adenovirus preparation with high yield and very low host cell protein (HCP) and DNA contamination, comparable to clinical grade pro...
What Makes A High-Quality Chromatography Resin?
The demand for resins for the manufacture of biological medicines is increasing every year. Walk through the process of what makes a high-quality chromatography resin.
What Is The DynaChrom™ Single-Use Chromatography System?
This chromatography system offers a flexible solution, paired with an advanced software platform, allowing easy integration with downstream process automation.
Chromatography Support Solutions
This video highlights Bio-Rad services including the development and optimization of purification platforms to meet today's manufacturing demands.
Challenges And Opportunities For Improved Chromatography Resins
Professor Giorgio Carta from the Department of Chemical Engineering at the University of Virginia gives an overview of recent advances in the development of resins for protein purification and in understanding protein-surface interactions that are responsible for separati...
Droplet Digital PCR Systems
Droplet Digital PCR (ddPCR) simplifies the quantification of host cell DNA in process development, quality control, and biomanufacturing processes.
Navigating The Diverse Antibody Pipeline With Chromatography Innovations
Choosing a suitable resin for your purification needs doesn’t have to be daunting. Learn more about how to select the right resin for your antibody variant purification project.
Redefine Your Oligonucleotide Manufacturing
Streamline oligo production and scale confidently. Explore high-performing, purpose-built automated equipment designed to ensure safety, efficiency, and purity, from synthesis through concentration.
A Scalable Immobilized Metal Affinity Chromatography Media For Process Purification
Downstream process purification of proteins requires a resin with optimized bead size for ideal pressure/flow properties and decent dynamic binding capacity DBC that provides production efficiencies and good process economics. This video explains how our newly developed m...
Resolute® BioSMB Multi-Column Chromatography
Learn how to achieve better resin utilization, minimize disruption to existing methods, and align your strategy with unique process goals.
Poster Review Non–Affinity Based Purification Platform for Neutral/Basic IgMs
Review the biological properties of IgM antibodies that make them very effective vehicles for in vitro diagnostics and therapeutics.
A Conceptual Overview Of The BioSMB MCC Platform
In this video, our technology expert Jason Forte describes how the BioSMB system offers 3-5 fold increase in productivity, yielding up to 80% savings on chromatography resin costs with minimal disruption to the accepted ways of doing chromatography today.
Intensified Virus Purification: Better, Faster, Virus Production
Viruses are widely used in many vaccines and therapies. Despite the difference in application there are similar process challenges. Learn how to overcome those challenges in this video.
Mobius® Chrom 20 System, For Purification Of Clinical And Process Scale Biologics
Our unique clamshell and single-use Flexware® clamshell assemblies offers ultimate ease of use.
Overview Of DoE Workshop At Bio-Rad
This video reviews a DoE Workshop that provided best practices and guidelines for DOE experiments using mixed-mode chromatography resins.
Perform Multiple Chromatography Steps On A Single System
The Resolute® BioSC platform is a highly modular multi-step chromatography system designed to purify biologics. The platform can be configured to design your own multi-step process.
Process-Scale Packing Guidelines: CHT™ Ceramic Hydroxyapatite
This video demonstrates proper packing technique, provides practical media handling tips, and gives specifications for optimal hardware and process conditions.
How To Select Your DSP Chromatography Technology?
Making the switch from single batch to multi-column chromatography can dramatically reduce resin utilization, costs and eliminate bottlenecks without sacrificing quality. This animated feature compares the traditional, single batch approach to a multi-column alternative f...
How To Select Your DSP Chromatography Technology
Watch to explore the differences between the conventional single-column batch method and the multi-column approach for mAb capture.
Explore Selectivity With Eshmuno® CMX Chromatography Resin
Eshmuno® CMX chromatography resin is a highly selective mixed mode chromatography resin for difficult to purify mAbs, ADCs and fusion proteins.
Meet The Experts: Part 1 - Process Analytical Technology (PAT)
Watch part 1 of this 4-part interview series to learn about process analytical technology (PAT) from expert Stacy Shollenberger.
Concentrate Your Product After One Path With Pellicon® Single Pass Tangential Flow Filtration
Discover Pellicon® Single-Pass Tangential Flow Filtration, the versatile ultrafiltration technology for process intensification.
Single-Use Centrifuge Cinematic
Gain a 360° view of the Thermo Scientific™ DynaSpin™ Single-Use Centrifuge.