Downstream Isolation and Purification Videos

DOWNSTREAM ISOLATION AND PURIFICATION

11:30

Addressing Manufacturability And Scalability Challenges In Multispecifics Purification

In this final segment from the Bioprocess Online Live event, “Challenges And Considerations For Purifying Multispecific Molecules,” our panelists answer some remaining audience questions relating to viral inactivation, affinity resins, precipitation s...

0:37

CaptureSelect Affinity Chromatography

30-second video sharing a visualization of our CaptureSelect affinity chromatography capability. The target protein binds with VHH molecules immobilized on the chromatography beads, non-target proteins are removed, and the eluted fraction contains a high yield of pur...

4:06

Solutions For Diverse Biomolecule Purification

Interview with Paul Lynch, Product Management Leader, Purification, discusses our chromatography resins and innovations in downstream purification processes.

5:05

Downstream Purification Symposium Overview

A focus on strategies for virus and monoclonal antibody purification, viral clearance, and aggregate removal challenges

5:50

MilliporeSigma Large Scale Capabilities Tour

A detailed look at MilliporeSigma’s new BioReliance® viral vector manufacturing facility and how we have employed the latest innovations and quality systems to deliver best-in-class gene therapy services.

3:47

Ensuring Quality, Driving Customer Confidence

How does quality assurance help drive scientific progress? A 30-year veteran shares her story of supporting customer needs and the development of groundbreaking new therapeutics.

3:25

Concentrate Your Product After One Path With Pellicon® Single Pass Tangential Flow Filtration

Discover Pellicon^® Single-Pass Tangential Flow Filtration, the versatile ultrafiltration technology for process intensification.

0:31

Transform Your Chromatography Processes With An Innovative Approach

Learn how to achieve better resin utilization, minimize disruption to existing methods, and align your strategy with unique process goals.

3:32

Tailoring Purification Solutions To Address Customer Challenges

Developing purification products for novel biotherapeutics requires close customer collaboration to ensure the tools do the job. Hear how these partnerships drive targeted innovation.

1:54

Chromatography Support Solutions

This video highlights Bio-Rad services including the development and optimization of purification platforms to meet today's manufacturing demands.

1:25

Overview Of DoE Workshop At Bio-Rad

This video reviews a DoE Workshop that provided best practices and guidelines for DOE experiments using mixed-mode chromatography resins.

2:16

Eshmuno® CMX ADC Polishing Animation

This animation demonstrates how Eshmuno® CMX Chromatography Resin removes undesired low DAR and high DAR species, enabling the best pharmacokinetics, efficacy, half-life and tolerability.

4:21

Perform Multiple Chromatography Steps On A Single System

The Resolute^® BioSC platform is a highly modular multi-step chromatography system designed to purify biologics. The platform can be configured to design your own multi-step process.

6:20

Strategies For Viral Inactivation And Filtration In Multispecifics

In this segment from the Bioprocess Online Live event, “Challenges And Considerations For Purifying Multispecific Molecules,” our panelists cover molecule sensitivity to low pH and the use of detergent-based viral inactivation, as well as evaluating t...

0:53

Your Roadmap For Efficient Processes

Struggling with mRNA integrity? Discover essential strategies to boost stability in mRNA manufacturing with innovative endonuclease-free DTT and Spermidine chemicals.

2:41

What Is The DynaChrom™ Single-Use Chromatography System?

This chromatography system offers a flexible solution, paired with an advanced software platform, allowing easy integration with downstream process automation.

2:34

Mobius® Chrom 20 System, For Purification Of Clinical And Process Scale Biologics

Our unique clamshell and single-use Flexware® clamshell assemblies offers ultimate ease of use.

3:26

CaptureSelect™ Technology - Powerful Affinity For More Streamlined Purification

Replace inefficient chromatographic steps with high-specificity affinity ligands to streamline downstream processing. This approach simplifies workflows and protects sensitive biomolecules.

28:06

Robust Workflow For Single Cell Cloning Of iPSCs For Making cGMP Master Cell Banks

We demonstrate a platform combination of Solentim instrumentation (the VIPS™) and soluble matrix (MatriClone™, based on laminin) for the high-efficiency, high-viability single-cell cloning of iPSCs to form the Master Cell Bank.

1:44

Master Your mRNA Manufacturing

Join pDNA and mRNA specialists as they discuss innovative mRNA manufacturing solutions for your purification challenges, mRNA stability, and overall product quality.

7:28

Multi-Product Manufacturing With Single-Use Chromatography

Gain insights into unparalleled flexibility in multi-product manufacturing with this single-use chromatography system to enable seamless scalability and process efficiency in your process.

2:57

A Scalable Immobilized Metal Affinity Chromatography Media For Process Purification

Downstream process purification of proteins requires a resin with optimized bead size for ideal pressure/flow properties and decent dynamic binding capacity DBC that provides production efficiencies and good process economics. This video explains how our newly developed m...

0:43

CTS DynaCellect Cinematic Overview

Achieve high cell purity and recovery with an automated, closed magnetic separation system. Learn how this technology helps increase robustness, minimize failures, and streamline cell therapy manufacturing.

7:43

Virus Clearance By Chromatography

This video features a presentation of the analysis of the over all performance of different chromatography types based on their internal database looking specifically for the log reduction factors for the most testable viruses; MuLV, MVM, PRV, and Reo-3.

0:44