
MAB PROCESS DEVELOPMENT AND OPTIMIZATION

The Technology Debate: Single-Use vs. Stainless Steel
In this discussion you will explore the multi-point case for adopting single-use technologies throughout the workflow via an economic, operational, and environmental sustainability lens.

Thermo Fisher Scientific Bio-Expo Live 2024: Upstream Bioprocessing: A Next-Gen Medium And Feed System
This presentation reviews next-generation cell culture media and feed options and a recent successful scale-up case study done in collaboration with Centre for Biochemical Engineering and Cell Cultivation Techniques at the Zurich University of Applied Sciences.

Considerations In Continuous Chromatography
In this segment of the Bioprocess Online Live event Bioprocess Intensification In The Real World, our presenters discuss considerations for continuous versus batch chromatography and compare notes on the approaches at their respective organizations.

Addressing Post-Translational Modifications In Novel Protein Therapeutics
Meinhard Hasslacher, Ph.D., Head of CMC at SOTIO Biotech, addresses an audience question on conjugation efficiencies in this segment of the Bioprocess Online Live event Early Process Considerations For Novel Protein Therapeutics. From there, we move on to an audience-led ...

Accelerating mAb Process Development In The Growing Therapeutics Market
The market for mAbs and mAb variants is growing rapidly. Explore the latest strategies and advancements in early stage mAb up- and downstream process development.

Cell Line Selection In Novel Protein Therapeutic Development
Lena Tholen, Ph.D., and Meinhard Hasslacher, Ph.D., weigh in early on important cell line selection considerations for novel protein therapeutics in this segment of "Early Process Considerations For Novel Protein Therapeutics".

Where Process Intensification Sits In The AbbVie, AstraZeneca Organizations
In this segment of the Bioprocess Online Live event Bioprocess Intensification In The Real World, panelists discuss where and how their roles in setting the course for process intensification sit within their greater organizations.

The Role Of Peptones In Boosting Quality And Yield
Peptones can significantly boost CHO cell bioprocessing. We analyze their impact on diverse CHO cell lines using real-world data to assess their effects on titer, protein quality, and cell growth.

Outsourcing Considerations For Novel Protein Therapeutics
Panelists discuss special considerations for outsourcing the development and manufacturing of novel, complex protein therapeutics in this Bioprocess Online Live event.

Efficient Downstream Processing Of Antibody-Based Therapeutics – A CDMO Perspective
Discover efficient downstream processing strategies for antibody-based therapeutics. Explore key considerations and trade-offs in purity, yield, speed, and cost, from a CDMO perspective.

Next-Gen Medium And Feeds System To Improve CHO Cell Line Productivity
Choose the right CHO medium and feed system to optimize your upstream processes and secure a seamless scaling up.

mAb Up- And Downstream Process Intensification Strategies
Discover how to reduce monoclonal antibody (mAb) manufacturing time and costs through process intensification. Learn about continuous perfusion, ultrahigh cell density banks, and more.

Scalable By Design: Streamlining Cell Culture Media Manufacturing
Learn ways to help improve quality, simplify technology transfer of proprietary media formulations, and mitigate logistical challenges associated with custom media scale-up processes.

What Analytics Drive Process Intensification?
Bioprocess Online Live panelists discuss the most fundamental analytics that inform and enable process intensification strategies in this segment of Bioprocess Intensification In The Real World.

Addressing Aggregation And Degradation In Complex Protein Therapeutics
In this segment of the Bioprocess Online Live event Early Process Considerations For Novel Protein Therapeutics, panelists discuss using a transient expression platform to make fast early product attribute decisions.

Why AstraZeneca and AbbVie Are Intensifying Processes
In this segment of the Bioprocess Online Live event Bioprocess Intensification In The Real World, our speakers share the motivation for continued process intensification in their respective organizations.

What Bioprocessing Bottlenecks Does Process Intensification Address?
Supply chains, consumables, and data are identified as three of the management challenges that intensified processes and process automation technology (PAT) are addressing at AbbVie and AstraZeneca.

Process Intensification Development Challenges At AZ and AbbVie
In this segment of the Bioprocess Online Live event Bioprocess Intensification In The Real World, panelists respond to audience questions about the challenges they’ve encountered while developing process intensification strategies.

Key Attributes To Monitor During Cell Line Development Of Complex Proteins
In this segment of the Bioprocess Online Live event Early Process Considerations For Novel Protein Therapeutics, panelists discuss key attributes to monitor during cell line development processes.

What's Next For Bioprocess Intensification?
Experts speaking on Bioprocess Intensification In The Real World wrap up the Bioprocess Online Live event with parting shots and reflections on the current state of process intensification and what the future holds.

IND Prep Versus Clinical/Commercial Scale-Up In Novel Protein Therapeutics
In this segment of the Bioprocess Online Live event Early Process Considerations For Novel Protein Therapeutics, panelists share detailed considerations for scale-up of complex protein therapeutics.

Upstream To Downstream: A Comprehensive Approach To AAV Production
How can you face the challenges of AAV production, scale up your AAV manufacturing effectively, and enhance the recovery and purity in your downstream processing.

Analytical Solutions To Help Accelerate Bioprocessing Success
Unlock the power of data-driven bioprocessing. Discover how advanced analytics can optimize your cell culture process, improve performance, and accelerate success.

Three Novel Protein Therapeutic Worldviews
In this segment of the Bioprocess Online Live event Early Process Considerations For Novel Protein Therapeutics, we meet panelists who share their topline perspectives on developing complex, novel protein therapeutics.

Thermo Fisher Scientific Bio-Expo Live 2024: Downstream Bioprocessing
Review downstream process tools from Thermo Fisher Scientific to enable optimal biologics purification, including chromatography resins, chemicals, process liquids, and buffers.

Process Liquids And Buffers Offering
Whether you are a researcher, scientist, or industry professional, this video will provide valuable insights into our large volume liquids manufacturing capabilities.

The Way Forward: Supply Chain Solutions
Learn how to build a resilient supply chain to navigate today's complex environment. Expert speakers share insights on optimization, innovation, and strategic planning to meet evolving market conditions.

Planning for Success: Supply Resiliency Strategies for Bench to Production
Build scalable material sourcing strategies for R&D and early phases through to commercialization and learn how to accelerate the development process and ensure the scalability of your biologics.

Scalable Production Of Lentivirus For Research To Commercial Manufacturing
Join our webinar on scaling the CTS LV-MAX System in bioreactors, covering transfection scalability, Thermo S.U.B. advantages, and DynaSpin’s efficient gene therapy integration.

Process Intensification Audience Q&A
Our panelists take audience questions on process intensification lessons learned from other industries.