mAb Process Development and Optimization

1. Thermo Fisher Scientific Bio-Expo Live 2024: Downstream Bioprocessing 8/15/2024

   Review downstream process tools from Thermo Fisher Scientific to enable optimal biologics purification, including chromatography resins, chemicals, process liquids, and buffers.

2. Why AstraZeneca and AbbVie Are Intensifying Processes 8/27/2024

   In this segment of the Bioprocess Online Live event Bioprocess Intensification In The Real World, our speakers share the motivation for continued process intensification in their respective organizations.

3. Upstream To Downstream: A Comprehensive Approach To AAV Production 12/7/2023

   How can you face the challenges of AAV production, scale up your AAV manufacturing effectively, and enhance the recovery and purity in your downstream processing.

4. Efficient Downstream Processing Of Antibody-Based Therapeutics – A CDMO Perspective 2/18/2025

   Discover efficient downstream processing strategies for antibody-based therapeutics. Explore key considerations and trade-offs in purity, yield, speed, and cost, from a CDMO perspective.

5. Planning for Success: Supply Resiliency Strategies for Bench to Production 10/18/2023

   Build scalable material sourcing strategies for R&D and early phases through to commercialization and learn how to accelerate the development process and ensure the scalability of your biologics.

6. What's Next For Bioprocess Intensification? 8/27/2024

   Experts speaking on Bioprocess Intensification In The Real World wrap up the Bioprocess Online Live event with parting shots and reflections on the current state of process intensification and what the future holds.

7. Considerations In Continuous Chromatography 8/27/2024

   In this segment of the Bioprocess Online Live event Bioprocess Intensification In The Real World, our presenters discuss considerations for continuous versus batch chromatography and compare notes on the approaches at their respective organizations.

8. The Technology Debate: Single-Use vs. Stainless Steel 10/4/2023

   In this discussion you will explore the multi-point case for adopting single-use technologies throughout the workflow via an economic, operational, and environmental sustainability lens.

9. Addressing Post-Translational Modifications In Novel Protein Therapeutics 9/13/2024

   Meinhard Hasslacher, Ph.D., Head of CMC at SOTIO Biotech, addresses an audience question on conjugation efficiencies in this segment of the Bioprocess Online Live event Early Process Considerations For Novel Protein Therapeutics. From there, we move on to an audience-led discussion on when to initially address titer, PTMS, and product quality during development of novel protein therapeutic cell lines, with Lena Tholen, Ph.D, Director of Cell Line and Bioprocess Development at FyoniBio and Neeraj Pakala, Ph.D. SVP of Product Development and Manufacturing at Vera Therapeutics weighing in.

10. Thermo Fisher Scientific Bio-Expo Live 2024: Upstream Bioprocessing: A Next-Gen Medium And Feed System 8/15/2024

    This presentation reviews next-generation cell culture media and feed options and a recent successful scale-up case study done in collaboration with Centre for Biochemical Engineering and Cell Cultivation Techniques at the Zurich University of Applied Sciences.