Thermo Fisher Bioproduction Insights

  1. High-Performance Extraction And Quantitation Of Host-Cell Residual DNA 6/19/2024

    This study presents a high-efficiency method for extracting and quantifying residual DNA from host cells using a semi-automated, high-throughput workflow.

  2. Maximizing Scale-Up Efficiency Of A mAb Upstream Process 6/17/2024

    This study demonstrated the effectiveness of a medium and feed system when tested at three different scales for its ability to high-quality, fed-batch monoclonal antibodies.

  3. Mycoplasma Testing In Monoclonal Antibody Production 6/17/2024

    Prevent costly disruptions in your bioproduction process. Discover how a PCR-based method can quickly detect the presence of mycoplasmas in raw materials, cell banks, and in-process and lot-release samples.

  4. Simultaneous Extraction Of Mycoplasma, MMV, And Vesivirus Nucleic Acids From A Single Sample 6/7/2024

    Achieve early detection of cell culture contamination with a nucleic acid extraction system to provide an integrated system for rapid and sensitive detection of mycoplasma, MMV, and vesivirus.

  5. Meeting Regulatory Requirements With Confidence 6/7/2024

    An outbreak of mycoplasma can halt a biopharmaceutical facility's production for months. Explore the impact of mycoplasma contamination and the most accurate and sensitive way to detect it.

  6. Residual Plasmid Quantification In Gene Therapy Manufacturing Workflows 6/7/2024

    This article details the design and application of a Plasmid DNA - Kanamycin Resistance Gene (pDNA-KanR) kit for residual plasmid quantification in gene therapy manufacturing.

  7. Optimize T Cell Phenotype With One-Step Isolation And Activation 5/10/2024

    This comparative bench-scale study features active-release beads that could improve the reliability, consistency, and longevity of cell therapy treatments.

  8. Overcoming Rapid Growth Challenges With Process Liquid Preparation 5/10/2024

    With a helpful assessment and the right process liquid preparation services, the CDMO featured in this study was able to find a path toward meeting the surge in demand for a client's therapeutic .

  9. Influence Of Peptones On CHO Glycosylation Profiles 5/10/2024

    This study explores the impact of nutrient availability and complexity on the glycosylation profiles of monoclonal antibodies (mAb) produced by different CHO cell lines.

  10. Identification Of An Extra Band In TLC Test Of Yeast Extract 5/10/2024

    Analyze the discovery and implications of a the discovery of a thin band, identified as tyramine and phenylethylamine, during thin-layer chromatography testing of yeast extract.