product datasheets, catalogs, app notes

  1. Chromatography Solutions For AAV Full And Empty Capsid Separation 3/1/2023

    Effective separation of full and empty AAV capsids requires implementation of purification strategies that differ from standard approaches used for traditional modalities. Explore two cases describing such approaches.

  2. Next Generation Sequencing For Adventitious Agent Detection In Cell Banks 2/23/2023

    NGS-based methods for agnostic broad range detection are suitable options to augment or replace current virus testing methodology. Explore a NGS AAT method for cell line characterization and more.

  3. Performing A Tangential Flow Filtration (TFF) Optimization Study 2/14/2023

    This application note describes the recommended methods and techniques for optimizing a tangential flow filtration (TFF) process using a Cogent® Lab system and the Bio4C® Control Software.

  4. Implementing High Cell Density Cryopreservation In Your Seed Train 1/22/2023

    Simplify seed train intensification with high cell density cryopreservation. Eliminate the need for manual scale-up steps and enable risk reduction through closed banking and inoculation processes.

  5. Capsules Versus Hollow Fibers For Ultrafiltration/Diafiltration (UF/DF) 1/13/2023

    Explore the performance evaluation of a first-of-its-kind spiral-wound TFF filter versus hollow fibers for UF/DF of viral vectors and the impact of either filter type on a TFF process.

  6. How Membrane Prefilters Enhance Bioprocessing Efficiency 12/14/2022

    Explore studies that highlight the benefits of prefiltration for increasing throughput capacity of sterilizing-grade filters challenged with streams containing a wide range of particle size distributions.

  7. Single-Use Tangential Flow Filtration Solution 12/13/2022

    Processing large batch sizes in one run using single-use equipment is a challenge. Learn about a system that has been specifically developed for large-scale tangential flow filtration.

  8. Impact Of DMSO And Freezing Technique In Upstream Bioprocessing 11/10/2022

    Integrating high cell density cryopreservation (HCDC) in the seed train means considering parameters like the choice of cryoprotectant and freezing technique.

  9. Implementation Of Raman Spectroscopy For In-Line Monitoring 11/3/2022

    Explore the development and implementation of Raman spectroscopy-based soft sensors for process monitoring of CPPs in bench scale, CHO cell, intensified seed trains (N-1).

  10. Middle-Up Mass Analysis Of Protease Digested Cetuximab 10/24/2022

    Explore a complete reversed phase UHPLC-MS workflow, developed to simplify middle-up mass analysis of an immunoglobulin G antibody, from the antibody purification, proteolysis, and reduction to its UHPLC-MS analysis.