Process Engineering STREAM

1. Clinical Trial Strategy And ADC Dev Partnership 4/29/2025

   As the Bioprocess Online Live panel discussion Accelerating ADC Process Development wraps up, expert panelists Dr. Léo Marx (Debiopharm), Dr. Monika Lamba Saini (ADC Therapeutics), and Dr. Philipp Spycher (Araris Biotech) address audience questions on AI-driven stratification of patients and biomarkers in clinical patient enrollment and IP strategies and collaboration.

2. AI In ADC Target Identification 4/29/2025

   How are AI and machine learning contributing to ADC target identification and early development? Dr. Monika Lamba Saini (ADC Therapeutics), Dr. Léo Marx (Debiopharm), and Dr. Philipp Spycher (Araris Biotech) tackle computational approaches to protein targets, clinical implications of target expression and internalization, and AlphaFold AI-driven pathology in this segment from the Bioprocess Online Live panel discussion Accelerating ADC Process Development.

3. Engineering Bacterial Vector-Based Immunotherapies With OS Therapies' Paul Romness and Robert Petit, Ph.D. 10/7/2025

   In this episode of “Better Biopharma,” host Tyler Menichiello is joined by OS Therapies’ CEO, Paul Romness, and chief medical and scientific officer, Robert Petit, Ph.D. The three discuss the development and manufacturing of the company’s lead asset, OST-HER2, a Listeria-based immunotherapy for osteosarcoma.

4. Challenges In ADC Process Development 4/29/2025

   Where does ADC process development fail? In this segment from the Bioprocess Online Live panel discussion Accelerating ADC Process Development, expert panelists Dr. Monika Lamba Saini (ADC Therapeutics), Dr. Léo Marx (Debiopharm), and Dr. Philipp Spycher (Araris Biotech) address audience questions on target identification cleanliness and payload challenges before we turn the tables on the audience with a question on their biggest challenges.

5. Regulatory And Biosafety Testing Expertise 3/31/2026

   Advancing biologics requires confidence in safety, quality, and compliance. Learn how integrated analytical and biosafety testing, backed by decades of expertise, helps reduce risk.

6. Inside Bioprocessing: Microbial Media 11/4/2025

   Learn the reasons why the animal origin-free trend in bioprocessing has taken so long to reach microbial bioproduction and the technical hurdles overcome during the development of Gibco CD Bacto Supreme.

7. When And How To Implement Process Intensification 10/3/2025

   Explore when to intensify your processes, what challenges to expect, and how to prepare for a successful transition with expert insights to help guide your strategy and ensure smoother implementation.

8. The Future Of Biomanufacturing: Innovating Process Intensification Together 7/1/2025

   Redefine your biomanufacturing by advancing process intensification technologies through strategic planning, innovation, and close customer collaboration to drive scalable and efficient solutions.

9. How To Improve API Solubility By Salt And Cocrystal Formation 3/4/2025

   Developing new APIs is complex and costly, especially with poor water solubility (BCS class II and IV). Explore techniques like salt and cocrystal formation to enhance solubility and bioavailability.

10. AI/ML As Tools In Biomanufacturing 9/17/2024

    In this segment from the Bioprocess Online Live, “A Realistic Look At AI/ML In Biomanufacturing,” our panelists kick off the conversation by discussing the ways AI/ML are being used as tools in biomanufacturing.