Downstream Chromatography

  1. A Practical Roadmap For Column Sizing, System Selection, And GxP Readiness 9/1/2026

    Chromatography scale-up depends on aligning different factors. Learn which factors can help maintain process consistency, manage risk, and support the transition from development to manufacturing.

  2. Chromatography Polishing In The Age Of Intensification 9/1/2026

    As upstream processes intensify, chromatography polishing must handle higher loads and evolving impurity profiles. Modern strategies can improve clearance, extend resin life, and maintain throughput.

  3. Build Process Robustness Through Deeper Process Understanding 8/27/2026

    Compare statistical, mechanistic, and machine learning approaches to understand their principles, requirements, and future potential for improving efficiency and supporting better decisions.

  4. mAb Aggregate Control On-Demand Webinar 5/22/2026

    Aggregation can undermine yield and quality in downstream mAb processing. Learn practical capture, polishing, and TFF strategies to prevent and reduce aggregates, with a focus on chromatography.

  5. Optimizing Antibody Variant Capture: Strategies To Combat Aggregation, Impurities, And Low Yields 2/26/2026

    Explore how process conditions affect bispecific antibody stability and impurity formation, as well as practical strategies to minimize aggregation and remove product‑related variants.

  6. Optimize Your mAb Capture And Polishing With The Latest Resins And Tips 6/26/2025

    Discover the latest innovations in monoclonal antibody purification and explore resin selection strategies to optimize product quality and improve process efficiency.

  7. Novel Chromatography For Antibody Variants And Recombinant Proteins 9/5/2024

    Watch to explore key considerations for developing purification processes for bispecific antibodies and learn about an innovative affinity chromatography technology for purifying any recombinant protein.

  8. Multi-Specific Antibody Development: What Challenges The Need For Speed? 8/9/2023

    In this segment of the Bioprocess Online Live event, Process Development For A Diverse mAb Pipeline, Bayer’s Sr. Director, Bioprocess Technologies, Amir Goudarzi, Ph.D., addresses why the industry is pursuing faster, more cost-effective multi-specific antibody development and some of the major challenges standing in the way of efficiency.

  9. How To Develop An Efficient Downstream Purification Process For bsAbs 5/1/2023

    Bispecific antibodies (bsAbs) have gained increasing interest in recent years. Learn how to develop an efficient downstream purification process for a cancer immunotherapy bsAb.

  10. Downstream Digital Twins. Biopharma Going In Silico 5/23/2022

    Statistical approaches like big data, machine learning, and artificial intelligence utilize statistics to predict trends and patterns. Mechanistic models are, instead, based on physical and biochemical principles.