Discovery STREAM

1. Validation Of An LCMS Hybrid Assay With EVOSEP Cleanup 2/17/2025

   By leveraging this innovative combination, the assay achieves detection limits comparable to traditional methodologies while enhancing overall efficiency and reliability.

2. Is Evaporation Important For Optical Biosensors? 2/17/2022

   If your sample is open to evaporation effects causing your concentration to change, will your data, and potentially your conclusions, be unreliable?

3. GLP And The Impact To Start Up Companies 4/18/2022

   Good Laboratory Practice is often used in laboratories and is necessary for specific investigations. What does it mean? And how can it help start-up companies? Watch this video to learn more.

4. Meet Your Bioprocess Sidekick For Cell Culture Media Analysis 6/10/2022

   You need rapid and reliable nutrient profiles to make informed decisions, and waiting on that data has detrimental effects on your process. See how REBEL fills the gap.

5. Don't Be A D**k With Ochre Bio's Dr. Quin Wills 9/27/2023

   Don't be offended by the title of today's Business of Biotech podcast. Dr. Quin Wills' application of what's become known as "Wheaton's Law" (look it up) is central to the ambitious goals his company, Ochre Bio, is pursuing: pioneering the value of computational biology in large mol discovery and development, putting an end to the global liver disease epidemic, and changing the costly, high-risk approach to clinical trials. On this week's episode, Dr. Wills and I explore how those goals are being addressed despite the challenges they present, and how the company's three guiding principles, don't be a d**k being one of them, align the Ochre team with the mission at hand. 

6. Testing Liquid Handler Performance With PCRMix 5/6/2022

   We demonstrate the importance of using an appropriate test solution when optimizing a liquid handler to dispense the master mix, a critical component in any PCR-based assay.

7. A Derivatization-Free LCMS Assay For 4β-hydroxycholesterol 1/23/2025

   Learn about a novel LCMS assay for 4β-hydroxycholesterol, a key biomarker for CYP3A activity. This derivatization-free method offers a faster and more efficient approach for clinical studies.

8. Can Kinetics Provide Detailed Information About Binding Interactions? 2/17/2022

   See the potential value kinetics brings to deepen the understanding of biological processes.

9. Functional Antibody Screening With Abalone Bio's Richard Yu, Ph.D. 7/29/2025

   In this episode of "Better Biopharma," Abalone Bio's CEO and co-founder, Richard Yu, Ph.D., explains how the company's functional antibody selection technology (FAST) platform differs from traditional affinity screening.

10. Development Of A Mitra Tip Extraction Assay Coupled With LC-MSMS 1/15/2025

    Watch this rundown of a novel method for quantifying L-Citrulline, L-Arginine, and L-Argininosuccinic acid using Mitra tip extraction coupled with LC-MS/MS for enhanced accuracy and reproducibility.