Cytiva Cell datasheets catalogs app notes

  1. CAR-T Cell Lentiviral Transduction By Spinoculation 5/21/2020

    There is a growing need to close and automate manufacturing of chimeric antigen receptor (CAR)-T cell therapies. Learn how to streamline this step while keeping flexibility during process development.

  2. Controlled Endpoint In Cryopreservation 2/24/2020

    Successful cryopreservation of cells requires a controlled cooling rate. Cooling too rapidly or too slowly could lead to a poorer outcome. This application note demonstrates how controlled-rate cooling is achieved using equipment such as VIA Freeze controlled-rate freezers.

  3. The Effect Of Rocking Rate And Angle On T Cell Cultures Grown In Expansion Systems 2/23/2020

    Ensuring optimal and maximal T cell production is critical for adoptive immunotherapy and its continued success. The Xuri Cell Expansion System is an important component of the clinical manufacturing process so we sought to investigate the effect of the rocking rate and angle on the expansion of T cells.

  4. Large Volume Cryopreservation: A Liquid Nitrogen Free Proof-Of-Concept 6/6/2019

    This study demonstrates a cell freezing protocol that uses the LN2-free VIA Freeze Quad controlled-rate freezer for the cryopreservation of up to eight cryobags and up to 560 mL total volume.

  5. Water-Free Vs Water Bath Cell Thawing 11/29/2018

    This benchmarking study compares the performance of the VIA Thaw CB1000 system and a water bath for thawing frozen cells.

  6. Consistent Cord Blood Cryopreservation 11/29/2018

    VIA Freeze controlled rate freezers are compact electrical systems that do not require liquid nitrogen for freezing cells. Conduction-based cooling enables consistent cryopreservation of cells, including those in umbilical cord blood.

  7. A Viable Alternative To Conventionally Freezing T Cells 8/30/2018

    Cryopreservation is near the end of an intensive and complex manufacturing process. This step is critical because some of the greatest technical and financial risks are incurred here.