KNAUER – Science with Passion

KNAUER manufactures in Germany high-end scientific instruments for research, routine analysis, quality assurance and other applications like the purification of active ingredients. Supported technologies include liquid chromatography (HPLC. UHPLC, FPLC, SMBC), precise handling and pumping of liquids up to high pressures (e.g. for sample preparation), as well as flow-through detection of dissolved substances for online monitoring. The latest development is lipid nanoparticle production equipment used in mRNA vaccine production.

Developing devices that help people in the lab gain new insights or facilitate their work - this is the spirit in which KNAUER was founded and continues to operate. As experts in liquid chromatography, we continue in the footsteps of our founder, Dr. Knauer. Together with scientists and other experts in the laboratory, we develop innovative and individual solutions. We are inquisitive and creative. This makes us the ideal partner for those who want more than a standard solution.

KNAUER is an established partner to the scientific community. We support research and technological progress today and in the future.

FEATURED INSIGHTS

Twist Of Two: 2D-LC For Oligos
Discover how coupling orthogonal mechanisms reveals hidden impurities and creates a more robust strategy for characterizing complex oligonucleotide samples.
A New Specialist For Oligonucleotides With Advantages
Discover how hybrid silica technologies ensure stability and high resolution in IP-RP chromatography applications while protecting instrumentation from excessive wear and tear.
The Secret To Pure Oligos: Why Anion Exchange Chromatography Rules At Scale
Discover how anion exchange chromatography delivers high loading capacity and clinical-grade purity while addressing common scale-up challenges like aggregation and equipment longevity.
How To Navigate Through The Jungle Of Columns?
Whether prioritizing mass spectrometry compatibility or loading capacity, understanding the specific trade-offs between IP-RP, AEX, and SEC methodologies is essential for successful characterization.
Size Matters: Mastering Size Exclusion For Oligos
Learn how to separate molecules strictly by size, effectively remove salts, and select the correct pore specifications for a gentle, non-destructive purification workflow.
Stick With Me: The Cool Chemistry Of HILIC Oligonucleotide Analysis
Discover a powerful alternative for analyzing polar sequences without ion-pairing reagents. By leveraging hydrophilic partitioning, you can achieve sharper separation and improved mass spectrometry compatibility.
The Sleek Science Of Ion Pair (IP)-Reversed Phase (RP) Oligonucleotide Analysis
Master oligonucleotide separation by balancing hydrophobic and ionic interactions. Learn how selecting the right cationic pairing agent optimizes retention and ensures compatibility with mass spectrometry workflows.
Charged For Action: The Hidden Secrets Of AEX Oligonucleotide Analysis
Understanding how to fine-tune pH and ionic strength allows for the detection of truncated sequences and single-nucleotide variants, turning complex purification challenges into reproducible data.
The Hitchhiker´s Guide To Creating Oligonucleotides From Start To Finish
Producing high-quality oligonucleotides demands precise execution across multiple stages. Gain a clearer understanding of the complete mid-scale production workflow and necessary quality control measures.

FEATURED INSIGHTS

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