ABOUT ENTEGRIS

In biopharmaceutical production, each instance where materials or products in development must be stored, handled, or transported presents a risk for breakage, contamination, and expensive product loss. In a modern, decentralized biopharmaceutical production line, materials and products must be kept frozen to ensure product safety, consistency, and shelf life. Because of these new realities, we face more production costs, logistics, speed, and complexity.

Bioproduction today has dramatically increased the value of product in each container. Production processes have been contracted out or may be taking place in different parts of the country or globe. At colder temperatures, containers have considerable limitations; traditional storage bottles are often more brittle at cold temperatures and can break easily, do not pack into containers or store in freezers efficiently and take longer to freeze and thaw due to their shape and volume. 

Entegris is in a unique position to help overcome these cold temperature challenges by offering assemblies designed for extreme cold and by partnering with qualified equipment manufacturers specializing in reliable, cold-chain containment. Let us help you gain control over your processes and reduce the potentially enormous financial risk to your valuable products. 

FEATURED PRODUCTS

The Entegris centrifuge bioprocess bag is designed to provide a closed and sterile solution for cell harvest and separation, reducing the risks associated with open handling and cleaning. Built with our proven film technology, the bags combine flexibility and durability with excellent gas barrier properties to ensure reliable performance. The single-use format simplifies operations, minimizes contamination risk, and supports consistent results across biopharmaceutical workflows.

At Entegris we need to innovate fast because you do. Our process delivers transformative solutions with dependable supply chains and process purity. Always with your patient outcome in mind.

Designed to fit into your process, our cartridge and capsule filters excel at filtering many common solutions including buffers, large and small volume parenterals, water, and ophthalmic products. Made to exacting specifications, our filters address contamination control needs within bioprocessing, cell and gene therapy, and pharmaceutical applications.

Whether you’re new to cold chain or a seasoned freeze/thaw pro, it can be difficult to find value-driven solutions for configuring freeze/thaw (F/T) biologic treatments and therapies. Complex cold chain demands are not one-size-fits-all and your team’s time is precious, which is why we created our Cold Chain Guidance Tool. This innovative tool guides you through common decision-making scenarios, analyzes your inputs, and provides you with an assessment of the biggest drivers to achieve optimal results from your process.

An entire assessment takes roughly 5 minutes to complete, and in the end, you’ll have a full report detailing your optimized cold chain configuration, including a handy reference on the results you can expect and a personalized link to contact us.

Aramus 2D single-use bags in custom shapes, sizes, and assembly configurations to optimize your process and meet your most challenging requirements.

Protect your high-value fluids with Aramus 2D bag assemblies and reduce the risk of product loss, contamination, or compromised quality.

VIDEOS

  • Learn practical strategies for optimizing harvest, cell separation, and large-volume freezing to ensure process efficiency, reduce risk, and maintain product viability.

  • Take advantage of our expertise in freeze/thaw. We have tools, expertise, and technologies in one place to enable you to make the right choices in refining your project.

  • Learn how to select the right sterile filtration solution for your specific single or multi-use life sciences applications with Chris Rios, Senior Field Applications Engineer.

  • Discover how can you select the best membrane and filter to meet all the requirements of your life science application.

  • Find out how to select a prefilter for sterile filtration applications and recognize the advantages between various membrane morphologies with Chris Rios, Entegris Senior Field Applications Engineer.

  • Discover sterile filter designs that minimize the amount of product loss that occurs from hold-up-volume during scale-up activities and at each stage of development and production.

  • Watch how our single-use mixing system creates a completely sterile mixing and recirculation process, ensuring your buffer and media are mixed correctly and efficiently.

  • Ross Acucena, applications director, and Donnie Beers, product manager, introduce our single-use mixing system made to be deployed rapidly to help manufacturers meet development, supply, and cost objectives.

  • Ross Acucena, applications director, and Donnie Beers, product manager, introduce our highly functional and adaptable microcarrier cell separation bags designed for single-use processes. 

  • This video demonstrates the Aramus™ 2D single-use bag assemblies reliability in a frozen drop test comparing the fluoropolymer bag to a polyethylene bag.

DATASHEETS & BROCHURES

  • Learn about a sterile, gamma-irradiated centrifuge assembly that features precision tubing and plugs, as well as detailed tolerances and material specs for reliable integration into workflows.

  • Learn about an innovative microcarrier and cell separation system that streamlines cell processing by delivering sterile performance through an easy-to-use setup that naturally fits into your workflow.

  • Achieve homogenous solutions rapidly with an innovative single-use system designed for sterile, closed mixing of powders and liquids, or liquid-liquid combinations.

  • The Entegris mixing system is designed to maximize simplicity, ease-of-use, and affordability. This single-use bag system creates a completely sterile mixing and recirculation process from start to finish.

  • Learn about the specifications and performance data for UPE vent capsule filters designed with a dual-layer hydrophobic ultra-high molecular weight polyethylene membrane

  • This solution reduces the risk of contamination by aseptically handling samples or aliquots of liquid that would normally have to be collected via open sampling methods such as conical tubes or vials.

  • Improve your handling, efficiency, throughput, and total cost of ownership in bulk-drug substance and cold-chain applications through a reusable, plastic shell solution.

  • This cell banking manifold kit can shorten your seed train process from weeks to days with manifolds that enable biomanufacturers to save time, money, and space while reducing contamination risks during upstream processing.

  • Receive the fluid handling benefits of customization, fast design, and delivery with quality assembly solutions.

  • Choose the correct bioprocess powder bag to serve as your operations containment and transfer solution, by reviewing the features, benefits, and specifications of this single-use option.

CONTACT INFORMATION

Entegris, Inc.

129 Concord Road

Billerica, MA 01821

UNITED STATES

Phone: 978 436 6500

Fax: 978 436 6735

Contact: Barry Westfall

FEATURED ARTICLES

WEBINARS