Newsletter | November 11, 2024

11.11.24 -- What's In The Leukopak Matters For Cell Therapy Manufacturing

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Accelerate Biologics Development With ATUM's Predictable discoCHO™ Platform

ATUM’s discoCHO™ platform merges discovery and development in a CHO-K1-based transient expression system, enabling early prediction of Critical Quality Attributes (CQAs) and reducing manufacturing risks. By producing proteins quickly and predictably, discoCHO shortens timelines, moving from sequence to protein in under four weeks. Its scalability and alignment with ATUM's miCHO stable platform provide robust production quality, enhancing efficiency in biologics development.

FOCUS ON UPSTREAM MANUFACTURING

What's In The Leukopak Matters For Cell Therapy Manufacturing

Advanced cell-based therapies are impossible without high-quality leukopaks from high-quality donors.

Scale-Up Of A Stirred-Tank Bioreactor Process For hMSC Manufacturing

See the results of our study to scale-up of a Xeno-Free (XF) fed batch microcarrier-based process for hMSC expansion in stirred tank reactors to the 50L scale.

Production Of A Highly Concentrated Monoclonal Antibody

Discover how you can achieve a final mAb concentration above 200 g/L while maintaining critical quality attributes.

Perfecting HEK293 Cells For Gene Therapy: The Role Of Incubator Flexibility

Discover how flexible incubator settings can significantly boost HEK293 cell growth and proliferation. Get expert insights on temperature, humidity, CO2 levels, and agitation for maximum yield.

Bispecific Antibodies Unleashed

Explore how leveraging expert CDMO partnerships can streamline the development process and enhance the efficacy of your bispecific antibody therapies.

Build Your Genome Engineering Toolbox For Success

Fast, efficient, and precise options for genome engineering are rapidly infiltrating the marketplace – the key to success is identifying the mechanism and tool(s) best suited for your goals.

Clarification Efficiency: Analyze The Bio-Separation Of CHO-S Cells

Could this single-use centrifugation be the solution to optimizing your clarification process by purifying and concentrating CHO-S cell feeds with low shear stress and minimal impact to cell viability?

Maintain Sterility And Ease In CGT Development, Including Cryopreservation

Sterile connectors streamline cell and gene therapy processes while maintaining sterility. By withstanding extreme temperatures and cryoprotectants, they can ensure product viability during cryopreservation.

Expand Your Toolbox For Quality mRNA Manufacturing

Explore guidelines for the use of SP6 RNA Polymerase in mRNA synthesis and your mRNA production processes.

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Webinar: Innovative Technologies to Accelerate Identification of High-Quality Clones

Cell line development faces challenges like critical quality attributes, data management, slowing progress and optimization. This webinar with Danaher explores strategies to tackle these issues using innovative technologies. Key topics include overcoming CHO cell line bottlenecks with the Cydem VT Automated Clone Screening System, accelerating charge variant identification, and enhancing laboratory execution in a data-driven environment to streamline CLD timelines. Click here to learn more.

UPSTREAM MANUFACTURING SOLUTIONS

Integrated Cell Line Development Solutions - Aragen Bioscience, Inc.

Which Organ-Chip Design Is Right For You? - Emulate

Multitron Incubation Shakers - Bring Your Bioprocessing To The Next Level - INFORS HT

Streamline Your Media Preparation and Column Packing - Asahi Kasei Bioprocess

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