White Paper

Expand Your Toolbox For Quality mRNA Manufacturing With SP6 RNA Polymerase


Explore guidelines for the use of SP6 RNA Polymerase in mRNA synthesis and your mRNA production processes. Similar to T7 RNA polymerase, SP6 RNA polymerase is a single subunit enzyme and does not require additional transcription factors to function. In these experiments, SP6 RNA Polymerase provided good yields using either Tris or HEPES-based IVT reaction buffers. Learn more about how these starting guidelines can be used to determine if SP6 RNA Polymerase is a good alternative for your specific template and optimize your process.

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