What Is DMPK, And Why Does It Matter In Drug Development?

By Lisa Postava, product marketing manager, preclinical & clinical, IDBS

Why do some promising drug candidates fail late in development, or worse, cause unexpected side effects after launch? Often, the answer involves their interaction with the human body – specifically, their metabolism and pharmacokinetics. Drug Metabolism and Pharmacokinetics (DMPK) is the scientific field dedicated to studying this exact relationship. It examines how the body processes a drug and how the drug moves through the system. These studies are vital for identifying potential safety issues, predicting how effective a drug might be, and avoiding dangerous interactions with other medications.

Essentially, DMPK provides a crucial safety and efficacy check early on. Want to learn precisely how DMPK achieves this and why it's indispensable? Continue reading to find out.