09.25.25 -- What Biotech Sponsors Should Look For In A CDMO For Sterile Fill/Finish

Review strategies to assess the potential for human immune response following the administration of an mRNA therapeutic, the associated LNP, and the protein encoded for by the mRNA.

Bispecific antibodies (bsAbs) offer transformative therapeutic potential through dual-target engagement, but their complex structure presents significant manufacturing challenges.

The complex biology of rare diseases creates unique hurdles, making it difficult to design and implement a drug development program. Explore the unique considerations for drug product manufacturing.

A principal concern of cell line determination is producing the desired protein in a considerable quantity. Understand the technical and regulatory considerations for microbial, mammalian, and yeast platforms.

Recent advancements in genetic engineering and analytical techniques have significantly enhanced E. coli's potential for protein expression.

Learn how an in vitro method for evaluating how different vaccine formulations affect antigen uptake by human dendritic cells can help advance the rational design of new subunit vaccines.

Explore strategies to improve the performance of IB processes as well as the pros and cons of soluble and insoluble processes: isolating, solubilizing, and properly refolding.