Newsletter | April 7, 2025

04.07.25 -- Using AI And ML To Gain Insight Into Optimal Glycoforms

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Webinar: Sustainable Manufacturing Through Efficient BioProduction Unit Operations

Join our webinar to explore sustainable bioprocessing solutions, tackling plastic waste with biobased consumables, process intensification, and optimized operations. Learn how seed train intensification, high-density cell banking, and efficient bioreactor scaling can reduce the environmental footprint. Gain insights from experts on implementing greener, more efficient workflows in biomanufacturing for a sustainable future. Click here to learn more.

FOCUS ON UPSTREAM MANUFACTURING

Using AI And ML To Gain Insight Into Optimal Glycoforms

Bioprocess Online asked Nathan Lewis, Ph.D., to briefly explain the research he presented at BPI West 2025.

Instant PAT Implementation Across Cell Lines, Media, And Scales

Explore how MAVERICK’s Raman-based technology delivers instant, reliable measurements of glucose, lactate, and biomass across diverse cell lines, media, and scales.

The Lab Partner You Can Count On: Multitron Incubator Shaker

The Multitron incubator shaker offers precision and efficiency for bioprocessing research, with pre-configured setup, compact design, ergonomic features, quiet operation, and hygienic design.

A Hybrid Approach For Optimizing Transient Protein Expression In CHO Cells

When choosing between protein expression formats such as transient versus stable pools, considerations include speed, cost, titre, and product quality.

Bioprocessing And Scale Up Of HEK293 Cells For AAV Production

Address your concerns with traditional viral vector production processes by using a scalable upstream AAV production platform solution for viral gene therapies.

Cell Culture Media Quality Control Strategies

Cell culture media quality is key for lab success. Learn essential sourcing, storage, and handling strategies to prevent contamination and costly setbacks.

Computational Fluid Dynamic Characterization Of Vertical-Wheel Bioreactors

Explore how computational fluid dynamics (CFD) characterize and scale-up vertical-wheel bioreactors, optimizing hydrodynamic conditions for effective induced pluripotent stem cell (iPSC) culture.

Electroporation Enables Efficient Antibody Discovery By Mammalian Display

Therapeutic antibody developers use mammalian display to identify promising candidates. Electroporation enables superior sequence diversity, enhanced library coverage, and streamlined workflows.

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The debate rages on. While the automation that enables continuous processing gets a lot of hype, there are plenty of dyed-in-the-wool biopharma pros who contend that process optimization and intensification yield comparable benefits, without requiring the capital-intensive process overhaul that continuous demands. Join Bioprocess Online Live for a virtual deep dive into the scalability, sustainability, and capital implications of the continuous-versus-optimized debate. Registration is free thanks to the support of Cytiva.

UPSTREAM MANUFACTURING SOLUTIONS

Robust Cell Line Development With Leap-In Transposase - ATUM

TransIT AAViator: A Transfection System Tailored For Maximal AAV Production - Mirus Bio

A Scaled-Down Solution For Simple, Robust Upstream Intensification - Repligen

Innovations In Transfection And Electroporation - Lonza

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Webinar: Sterile Gas Filtration and Optimization in Bioprocessing

This webinar will explore the role of sterilizing-grade gas/vent filters in bioprocessing, highlighting their function as sterile barriers using hydrophobic membranes. Join Entegris as they address challenges like premature fouling and key factors affecting performance, such as flow rate, membrane type, and system design. Their experts will discuss optimizing filter selection to enhance efficiency, cost-effectiveness, and scalability in critical bioprocessing applications. Click here to learn more.

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