By Hendrik Adams, Wannie Horrevoets, Elina Kleijs, Jenny England, Alejandro Becerra, Jessica de Rooij, Pim Hermans, Marien Vis, Frank Detmers
For decades Protein A chromatography has been the method of choice for the purification of monoclonal antibodies. Modifications to the first generation of Protein A ligands has given way to more robust and efficient purification resins allowing the design of antibody purification processes with greater flexibility. With the introduction of Thermo Scientific™ MabCaptureC™ affinity matrix, a new Protein A resin now is available. Featuring high capacity and a highly cross-linked agarose backbone, this Protein A resin is specifically designed to help improve the productivity and efficiency of your antibody purification process.