Newsletter | September 15, 2025

09.15.25 -- Unpacking Pfizer's Advanced Process Control Platform For Upstream Ops

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FOCUS ON UPSTREAM MANUFACTURING

Unpacking Pfizer's Advanced Process Control Platform For Upstream Ops

Pfizer's advanced process control platform gives modelers more dexterity compared to default controllers, thus speeding up process development.

CDMO Hunger Games And The State Of Biotech With Siren Biotechnology's Nicole Paulk, Ph.D.

Biotech leader Nicole Paulk, Ph.D., joins “Better Biopharma” to discuss Siren Biotechnology’s switch from plasmids to producer cell lines, CGT funding challenges, and the competition that determined which CDMO won Siren’s business.

Developing A Scalable Protocol For T Cell Activation, Expansion

Learn about a scalable protocol for T cell activation and expansion. This approach ensures robust T cell growth, viability, and memory phenotypes for clinical applications. 

Cell Culture Media Quality Control Strategies

Cell culture media quality is key for lab success. Learn essential sourcing, storage, and handling strategies to prevent contamination and costly setbacks.

Bioconversion Of Babassu Mesocarp Flour Into Single-Cell Protein

Understand how the continuous feeding of babassu hydrolysate to yeast cultures can efficiently transform a byproduct into a protein-rich ingredient for plant-based foods.

De-Risking CHO Cell Line Development With Automation, Predictive Modeling

Discover how high-throughput, single-cell technologies combined with machine learning and automation are transforming clone selection to accelerate timelines and improve accuracy in bioprocessing.

Metabolic Phenotype Preservation And Suitability Of hMSCs

Learn how researchers demonstrated scalable hADSC expansion in stirred-tank bioreactors using microcarriers, achieving metabolic stability and consistent growth for cell therapy applications.

Unlocking The Potential Of Gamma Delta T Cell-Based Therapies

Learn more about two unique methods for clinical-scale expansion of gamma delta T cells, which are well suited for a wide variety of treatments due to their reduced risk of graft-versus-host disease.

Simplified LV And AAV Clarification With Tangential Flow Depth Filtration

Learn how Tangential Flow Depth Filtration (TFDF) enhances viral vector production, streamlining the clarification process and increasing efficiency and yield for LV and AAV manufacturing.

Computational Fluid Dynamic Characterization Of Vertical-Wheel Bioreactors

Explore how computational fluid dynamics (CFD) characterize and scale-up vertical-wheel bioreactors, optimizing hydrodynamic conditions for effective induced pluripotent stem cell (iPSC) culture.

From R&D Tool To GMP Solution: Is Glycoengineering Ready For Your Plant?

In this assessment of the in vitro glycoengineering technology we determine if it is suitable for the development, manufacturing, and analysis of therapeutic proteins.

Cell Expansion System Supports Proliferation Of Regulatory T-Cells

This study showcases a cell expansion system that is providing T-cells with an ideal environment for growth, efficient in expanding many cells quickly, and enhancing regulatory T-cell characteristics.

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Webinar: Next-Generation MSC Therapies: Advancing Treatment for GvHD

Join this Corning Life Sciences webinar to explore an innovative approach for enhancing mesenchymal stromal cell (MSC) therapy in graft-versus-host disease (GvHD). Learn how genetically engineered Ad-MSCs co-expressing CXCR4 and IL-10 demonstrated superior migration, immune modulation, and therapeutic benefit in preclinical models. Plus, discover how Corning® HYPER technology enables efficient GMP-scale production for clinical applications. Register now to secure your spot! Click here to learn more.

UPSTREAM MANUFACTURING SOLUTIONS

A Cell Line Portfolio For AAV Manufacturing - Cytiva

Advanced Tubing Retainers: Pharma+ - Nordson MEDICAL

Rapidly Transfect Cells With Scalable Electroporation Technology - MaxCyte, Inc.

Discover A Platform For Antibodies With Increased ADCC Activity - ATUM

Krakatoa™ Benchtop Media Maker - Nucleus Biologics

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