Tulip Tank Case Study: The Unrecognized Role Of Mixing During TFF

The consistency of the feed delivered to filtration systems plays a pivotal role in the overall efficiency and reliability of tangential flow filtration (TFF) processes. However, this factor is frequently underestimated. Even minor fluctuations in feed composition can lead to significant performance deviations, particularly during sensitive stages like diafiltration. These inconsistencies can compromise product quality, increase processing time, and reduce yield. Delves into how mixing dynamics directly influence TFF outcomes. By integrating an innovative single-use Tulip Tank with the KrosFlo® RS 30 TFF system, researchers observed a marked improvement in system performance compared to traditional retentate vessels. This combination not only enhanced mixing uniformity but also narrowed the gap between theoretical process models and real-world results, leading to more predictable and efficient filtration.

If you're looking to optimize your TFF workflows and reduce variability in your bioprocessing operations, explore how advanced mixing solutions like the Tulip Tank can elevate your system’s performance.