07.07.25 -- The Promise And Challenges Of Cell-Free Protein Systems

A new chemically defined fed-batch bioprocess medium simplifies hMSC-EV production, increasing yields by 2-4x while maintaining EV quality across donors and tissue types in scalable GMP environments.

Compare expansion parameters when adherent cells are cultured on the small and standard bioreactors using a hollow-fiber bioreactor platform.

The transition from manual to automated cell processing is vital for therapeutic success. A versatile, single-use system simplifies operations, reduces variability, and ensures product quality throughout manufacturing.

Optimize your bioprocessing harvest with single-use centrifugation. Reduce costs, waste, and space needs compared to traditional depth filtration methods.

Explore the key principles of process intensification as a strategy for improving the efficiency and productivity of biologics manufacturing, including process modeling, control, and advanced analytics.

How can you leverage flow electroporation technology to drive your biologics development forward and deliver gram-scale transient protein production within two weeks?

Explore how innovative bioreactor technology enables consistent and efficient scale-up of human induced pluripotent stem cells (hiPSCs) from 100ml to 3L, ensuring optimal cell yield and quality.

Multi-well inserts allowing for a two-chamber system that can expose cell cultures from above and below provide greater versatility and expand research options compared to standard cell culture plates.

Learn how this game-changing platform simplifies the complex process of custom media design, empowering researchers to expedite their development and achieve optimal results.

Scaling up life-saving gene-edited cell therapies means tackling production inefficiencies. Overcoming the time-consuming and risky cell washing step is crucial for clinical and commercial success.

This article examines the role of sample sizes in the determination of cleaning process capability or process performance in the manufacture of drugs/therapies and medical devices.