|
|
|
|
|
|
|
|
Sterile manufacturing is increasingly a strategic differentiator in drug development, particularly as antibody-drug conjugates (ADCs) add complexity to formulation, fill/finish, and lyophilization. This collection explores critical decisions around in-house manufacturing, outsourcing, and CDMO selection, alongside ADC-specific lyophilization challenges. Technical perspectives on process development, cycle optimization, controlled ice nucleation, drying, and automated visual inspection offer practical guidance for improving efficiency, consistency, and product integrity while reducing risk and accelerating progress toward commercialization. Learn more
|
|
|
|
|
|
|
|
Lipid Nanoparticles For Pulmonary Delivery Of mRNA
|
|
Poster | By Sams M. A. Sadat, Vicente Lacap, Richard Jiang, et al., Cytiva
|
Gain insight into how nebulized mRNA lipid nanoparticles show preclinical success in lung delivery, offering fresh momentum for inhaled gene therapies targeting respiratory diseases.
|
|
|
|
|
|
GLP-1 INJ Solid Phase Peptide Synthesis (SPPS) Workflow
|
|
Poster | ILC Dover, An Ingersoll Rand Business
|
Scale your GLP-1 peptide synthesis efficiently. Discover how automated solid-phase workflows and single-use fluidics maximize crude purity while reducing total solvent consumption.
|
|
|
|
|
|
Automated Fill And Finish For Cell Therapy
|
|
Application Note | CellBri
|
Automated fill-finish systems protect sensitive cell therapies using low-shear handling to maintain dose uniformity, cell viability, and process consistency across every batch.
|
|
|
|
|
|
Early-Phase Injectable Formulation Development
|
|
White Paper | Thermo Fisher Scientific
|
Examine how expert-driven strategies and data-centric tools can help you overcome formulation challenges and accelerate the development of stable, high-performance injectable therapeutics.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Bio-Expo Live Downstream Manufacturing Session is a virtual event for biopharma professionals focused on downstream manufacturing solutions. Attendees can discover new equipment and technologies supporting therapeutic areas from ADCs to vaccines through short, interactive presentations with live Q&A. The event is tailored for biopharma companies and contract manufacturers seeking solutions to overcome downstream manufacturing challenges. Register now to reserve your spot!
|
|
|
|
FOCUS ON DOWNSTREAM MANUFACTURING
|
|
|
|
|
|
By Bioprocess Online Live
|
This virtual panel discussion featured David Scherr, Ph.D., a senior scientist in bioprocessing technologies and engineering at AstraZeneca, and Vadim Klyushnichenko, Ph.D., VP biopharmaceutical development and quality at Calibr-Skaggs Institute for Innovative Medicines. Scherr and Klyushnichenko discussed where productivity gains can be achieved and how development teams can improve process performance by simplifying purification strategies and reducing chromatography steps.
|
|
|
|
|
|
|
|
Challenges And Solutions In Lyophilization Development For ADCs
|
|
White Paper | By Gregory Sacha, Ph.D., Simtra BioPharma Solutions
|
Successful ADC lyophilization requires a robust, individualized process driven by thermal characterization using DSC and FDM to define the critical parameters for stability and efficient manufacturing.
|
|
|
|
|
|
|
|
|
|
Unlocking Robust Separations For Modern Peptide Therapeutics
|
|
Application Note | By Emery Domain, Caitlin Hanna, and Steve Shiner, Waters Corporation
|
As peptide therapeutics grow more complex, impurity profiling demands greater chromatographic confidence. See how robust reproducibility can support reliable GLP-1 receptor agonist analysis.
|
|
|
|
|
|
Titer Analysis In The Era Of Complex Antibody Therapeutics
|
|
Article | By Kelly Flook, Ph.D., Thermo Fisher Scientific Bioproduction
|
As antibody formats grow more complex, titer is harder to measure. Chromatography cuts through matrix noise to deliver accurate, scalable quantification from early development through QC.
|
|
|
|
DOWNSTREAM MANUFACTURING SOLUTIONS
|
|
|
|
|
|
|
| Connect With Bioprocess Online: |
|
|
|
|
