Newsletter | August 18, 2025

08.18.25 -- The Latest On CRISPR Deployment In TIL Therapy Development

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The Latest On CRISPR Deployment In TIL Therapy Development

Here’s a quick look at how CRISPR’s emerging as an enhancer to improve TIL pharmacokinetics, efficacy, and tolerability without disrupting production.

Cell Culture Media Change Protocol

Keep your cells thriving. Learn the essential cell culture media change protocol, including frequency, steps, and tips for optimal cell growth. Discover best practices and avoid common pitfalls.

Quicker Development Using Cell Line Integration, End-To-End Support

Despite challenges with mammalian host cell line diversity, Lonza's mitigation strategies drive efficiency and reproducibility, maximizing cell growth and product quality.

De-Risk Your Path To Clinic With An AAV Suspension Platform

Build a reliable, de-risked path to the clinic while avoiding unforeseen costs and compliance-related delays with advice from Suparna Sanyal, PhD, Head of Viral Vectors Commercial Development.

Advances In Custom Medium Development: The Multi-Omics Difference

Spent media analysis continues to be an essential part of many media development workflows. Newer techniques, however, using state-of-the-art analytical technology, are becoming more popular.

Assessing mAb Quality Through Direct Spent Media Analysis

Learn about an innovative tool that offers direct analysis of spent media, revealing key product quality attributes (PQAs) of monoclonal antibodies (mAbs) that ensure optimal mAb quality and productivity.

Clinical-Scale Expansion Of Peripheral Blood Derived γδ T Cells

See how billions of γδ T cells can be generated from peripheral blood mononuclear cells with a chemically defined, non-animal origin, serum-free medium in a rocking motion platform.

Transposase-Enabled CLD: From Transfection To High Titer With Ease

Gain insight into the benefits of a next-generation CLD platform that delivers consistent quality, scalable performance and flexible expression solutions tailored to the demands of complex molecules.

Ex Vivo Expansion And Differentiation Of Erythroblasts

Compare and contrast the performance of two stirred bioreactor types during the expansion of erythroblast cultures when a repeated batch cultivation strategy was used.

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The PDA Pharmaceutical Microbiology Conference 2025 marks two decades of advancing microbiological science and practice. This milestone event brings together the global microbiology community, including experts from industry, academia, and regulatory agencies, to explore the evolving landscape of pharmaceutical microbiology. This year’s theme, Microbial Resilience: Today’s Response, Tomorrow’s Plan, reflects our focus on navigating present-day challenges while building robust strategies for the future.

UPSTREAM MANUFACTURING SOLUTIONS

Advantages of Vertical-Wheel Bioreactors For High-Yield Expansion - PBS Biotech, Inc.

Single-Use Bioreactors For Cell Culture, Fermentation, And Manufacturing - Eppendorf SE

Master Your mRNA Manufacturing - MilliporeSigma

Bio-Expo Live February 2025: Upstream Bioprocessing - Mirus Bio

J.T.Baker® Cell Lysis Solution And J.T.Baker® Endonuclease - Avantor

Biologics Discovery, Development, And Manufacturing - Curia

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