Newsletter | June 8, 2026

06.08.26 -- The Hidden Engineering Behind Successful Upstream Bioprocessing

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Webinar: Breaking the CLD Bottleneck: Generate Stable High-Producing Clones in 14 Weeks

Accelerating cell line development is critical as monoclonal antibody modalities grow more complex. In this webinar, Thermo Fisher Scientific explores how the Gibco™ CHOvantage™ GS CLD kit enables rapid generation of stable, high-producing CHO cell lines for mAbs, bispecific antibodies, and fusion proteins. Learn how the platform delivers scalable performance, high titers, and stability to help streamline development. Click here to learn more.

FOCUS ON UPSTREAM MANUFACTURING

The Hidden Engineering Behind Successful Upstream Bioprocessing

By Smiriti Gupta, NIRAS

In upstream biopharmaceutical production, manufacturing is inseparable from biology, engineering, contamination control, and quality science.

Rapid Production Of Assay Ready Cells For GPCR Drug Discovery

Application Note | MaxCyte, Inc.

Accelerate drug discovery by leveraging transiently transfected assay-ready cells. This method improves assay sensitivity and reduces variability for GPCRs.

Produce MSC-Derived Cell Therapies From Isolation To Large-Scale

White Paper | By Tom Bongiorno, Whitney Cary, Irana Coletti, et al., Corning Life Sciences

Drive successful MSC therapy development by optimizing isolation methods, surface chemistry, and closed-system expansion technologies to ensure cellular stability and commercial scalability.

The Science Fueling Cell Culture Optimization For Biologic Therapies

Poster | Thermo Fisher Scientific

Boost mAb titers by over 60% with an optimized intensified fed-batch process, no new equipment required. Gain insight into the data.

Mammalian Cell Line Development

White Paper | WuXi Biologics

Explore how modern cell line engineering boosts speed, stability, and scalability across biologics, with practical insights to cut risk and improve readiness for downstream development.

Optimizing Biotherapeutic Protein Expression With CHO Vector Technology

Webinar | Lonza

Review the development of a high-strength synthetic gene promoter that enhances titers while maintaining exceptional product quality and expression stability, to support efficiency.

Efficient FBS Removal And Cell Concentration In Vero Cell Cultures

Application Note | CARR Biosystems

Learn about the benefits of an instrument that is showing potential to optimize Vero cell culture processes through concentration and FBS removal using PBS as the wash solution.

UPSTREAM MANUFACTURING SOLUTIONS

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Achieve Titers Up To 6E15 vg/L With A Modular Tool Suite - Asimov

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Complete Cell Culture Media Solutions For Primary Mesenchymal Stromal/Stem Cells - FUJIFILM Biosciences

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Enabling Advanced Bioprocessing: Solutions That Challenge The Status Quo - Repligen

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Webinar: From Variable to Predictable: How Intensified Upstream Processing Improves Scale-Up and Tech Transfer

Discover how intensified upstream processing can help biomanufacturers boost productivity, reduce variability, and accelerate timelines without compromising quality or compliance. In this webinar, Thermo Fisher Scientific experts share practical strategies for high-density inoculation, perfusion, automation, PAT, and data-driven control to improve consistency, streamline scale-up, and enable reliable tech transfer across development and GMP manufacturing. Click here to learn more.

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