Newsletter | October 13, 2025

10.13.25 -- Survey: 30% Of Biopharmas Cite Cost, Productivity As Top Priorities

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Turning Agricultural Byproducts Into Protein-Rich Food Solutions

BiOinFood achieved a 50% biomass increase and 15% yield improvement by converting babassu mesocarp flour into single-cell protein using the INFORS HT Multifors bioreactor with eve® software and Minitron incubator shaker. Optimized fed-batch yeast cultivation produced protein-rich biomass, successfully tested in plant-based burger prototypes. Discover how INFORS HT enables efficient bioprocessing and sustainable upcycling of agricultural byproducts into functional food ingredients. Download the full application note today.

FOCUS ON UPSTREAM MANUFACTURING

Survey: 30% Of Biopharmas Cite Cost, Productivity As Top Priorities

Both focus areas aim at the same outcome, stronger economics and sustainable competitiveness, according to BioPlan Associates' 22nd Annual Biomanufacturing Report.

Bioprocess Operation Modes And Advanced Bioreactor Technologies

Explore innovative cell culture methodologies and bioreactor technologies to optimize productivity, enhance product quality, and drive efficiency in biotechnological applications.

Harnessing Amino Acid Derivatives To Improve Monoclonal Antibodies

Recent research in the growing monoclonal antibody (mAb) market identifies excipients that reduce the viscosity of high-concentration formulations and improve stability across a wide concentration range.

Strategies For Intensified Viral Vector Production In HEK293 Cell Culture

Learn a strategy for scalable bioprocessing and media optimization that drives intensified viral vector production. Achieve high cell density, excellent viability, and consistent AAV titers from 50mL to 5L.

An Alternative Genetic Engineering Tool In CHO Cells

Learn how transposon technology is being reimagined as a genetic engineering tool to create high-performing CHO cell lines for biotherapeutic production with enhanced metabolic and glycan profiles.

Modular Facilities With Smaller Footprint Through Dynamic Perfusion

Discover how a top CDMO leveraged dynamic perfusion technology to boost biomanufacturing throughput, cut capital costs, and enable flexible, multi-modality production.

High Power Mixing At Large Scale: Magnetic Mixer System Overview

Explore the advantages of 2000 and 3000 L single-use mixing systems and experimental results demonstrating their capacity to deliver high power at large scales and flexibility for use at lower volumes.

Next-Generation Cell Therapy: Eliminating Thermal Shock In Electroporation

Conventional electroporation methods struggle with damaging heat buildup. Discover how innovative flow technology leverages physics to protect cells and enable large-scale therapeutic production.

Continuous Monitoring And Control Of Glucose And Lactate

This experiment demonstrates that continuous real-time monitoring of glucose and lactate and dynamic glucose feed control to a low-level set-point leads to improved process and product parameters.

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Webinar: Enabling Continuous Process Intelligence: In-Line PAT Solutions for cGMP Environments

Boost efficiency and compliance in bioprocessing with Repligen’s upcoming webinar on process analytical technology (PAT). Explore real-world applications of the FlowVPX® and MAVERICK® systems for real-time monitoring of critical parameters, smarter decision-making, and reduced costs. See how PAT streamlines upstream and downstream workflows, accelerates production, and supports GMP compliance—all while cutting deviations and saving valuable time. Click here to learn more.

UPSTREAM MANUFACTURING SOLUTIONS

Cell Therapy - Pushing The Limit - BD Biosciences

PHCbi's Microbiological Cooled Incubator: MIR-554-PA - PHC Corporation of North America

Unlock Your Manufacturing Potential With Scalable Glycoengineering - Roche CustomBiotech

VirusGEN Complex Stabilizer: Scale AAV Production With Peace Of Mind - Mirus Bio

Empower Your Bioprocess Journey With Innovative Solutions - Eppendorf SE

Cell & Media Kits - RoosterBio

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Webinar: Smart Media Screening & Design: Saving Time and Boosting Titers

Choosing the right culture medium is crucial after cell line development but can be challenging. Join this webinar to explore case studies, high-throughput screening, and strategies for selecting or designing optimal media and feed formulations—helping you save time, improve performance, and accelerate development. Click here to learn more.

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