Streamlining Vaccine Development And Production With Modality-Specific Purification Tools For mRNA And Beyond

The impressive speed of COVID-19 vaccine creation, production, and deployment was fueled by novel vaccine modalities and significant progress in downstream purification tools. These crucial advancements continue to accelerate the search for vaccines against other persistent infectious agents, like HIV and malaria.

Modern purification techniques are essential for rapid candidate screening and intensifying the downstream processing of diverse vaccine formats, including mRNA, viral vector vaccines, and virus-like particles (VLPs). For example, C-tag technology offers a superior alternative to His-Tag for easy candidate screening. Furthermore, adopting advanced affinity and ion exchange chromatography resins can drastically improve the purification of these next-generation modalities, optimizing processes for both protein-based and nucleic acid-based vaccines. Understanding the tools available for each platform is key to ensuring a robust and efficient vaccine pipeline.

Discover how to leverage these specific tools to accelerate your vaccine development pipeline.