Newsletter | July 14, 2025

07.14.25 -- Sorriso's Path To Oral Biologics Dosing Is Through The Gut

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Webinar: Enhancing Protein Quality Through Optimized Galactosylation

Whether you are looking to modify your existing cell culture process or seek solutions to expedite your product's time-to-market, this webinar provides the knowledge and tools you need to achieve your desired protein quality. Learn the importance of proper glycosylation in achieving consistent, desirable protein quality as well as strategies to control and optimize galactosylation profiles in various cell culture processes. Click here to learn more.

FOCUS ON UPSTREAM MANUFACTURING

Sorriso's Path To Oral Biologics Dosing Is Through The Gut

Following positive results from a Phase 1b trial, company leaders describe scaling their yeast expression and spray-drying processes as they prepare for Phase 2.

Comparing Activation Methods To Yield Clinical-Scale Expansion Of T Cells

Data from the use of two distinct methods to generate billions of gamma delta T cells from peripheral blood mononuclear cells (PBMCs) is compared.

What Is Transfection?

Learn about the process of transfection and why it is crucial for studying gene function and has applications in various fields, including drug development and gene therapy.

Cost And Scalability Key Drivers Of Expanded Gene Therapy Access

Gene therapies are expanding beyond rare diseases, but high costs hinder access. Discover how innovations in viral vector manufacturing could make these breakthroughs more affordable.

In Vitro Glycoengineering — Suitability For BioPharma Manufacturing

In this assessment of the in vitro glycoengineering technology we determine if it is suitable for the development, manufacturing, and analysis of therapeutic proteins.

Best Practices For Scaling PSC Expansion

Achieve robust PSC expansion with proven best practices. This session covers single-cell passaging, perfusion feeding, and in-vessel harvesting to streamline your process for efficient, linear scale-up.

Leveraging Novel Analytical Approaches For Advanced Therapies

Review the advantages and limitations of transcriptional assays versus reporter gene assays and how the transcriptional assay compares to ddPCR and flow cytometry for analysis of CGTs.

What You Paste Matters

Explore the use of transposase/transposon systems in the biotech industry, particularly in the development of stable cell lines for protein manufacturing.

N-1 Perfusion High Inoculum Fed-Batch For Reduced COGS And Easy Retrofit

A mid-to-large biopharma wanted to increase productivity 2-3 times in their fed-batch facility and also reduce their current cost of goods (COGS). With one small change in the upstream (USP) seed train, the customer was able to meet their goals.

Overcome The Limitations Of Conventional Transfection With Electroporation

Learn how electroporation technology improves gene editing efficiency, reduces cell death, and enables scalable workflows for cell therapy, screening, and bioproduction in this informative webinar.

Bioreactor Preparation Solutions

Embrace optimized bioreactor preparation for efficient cleaning and sterilization to reduce labor, ensure reproducibility, and support pharmaceutical manufacturing through pre-validated processes.

Cell Harvesting: Optimizing Viability And Recovery In Cell Therapy

Learn about a family of centrifuges and review of data collected on the centrifuges' performance for the harvest of cells in cell therapy production.

UPSTREAM MANUFACTURING SOLUTIONS

CellShot® Technology: Partitioned Flow Electroporation - Femtobiomed Inc.

Choosing A Mycoplasma Detection Strategy - Bio-Rad Laboratories, Inc.

Advanced Tubing Retainers: Pharma+ - Nordson MEDICAL

Quantum Flex: The Next Generation Of Cell Expansion - Terumo BCT

SPONSOR

Webinar: Mitigating Global Disruptions With Redundancy In Upstream Cell Culture Media Supply

Potential delays or shortages in securing critical raw materials can impact production timelines and efficiency — threatening the pharmaceutical industry's ability to meet global health needs. Learn best practices around outsourcing, primary and secondary media supply and how Thermo Fisher is helping ensure consistent Gibco™ media quality and on-time delivery on a global scale. Click here to learn more.

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