"Roosters Bearing Gifts" To Solve Ex Vivo Gene Delivery Challenges

By Jon Carson, Terri Willstaedt, & Mary Doolin

Read through the tricky challenge of gene transfer into primary cells and the quest to build a reliable “Trojan Horse” for ex vivo gene therapy. Three industry experts discuss developments in technology to solve the challenges of viral and non-viral cell engineering for advanced therapies including:

• The Impact of Genetic Engineering on the Next Wave of Cell and Exosomes Advanced Therapies
• Transduction Amplification with RoosterGEM™
• Non-viral transfection and AAV Transduction with RoosterGEM

RoosterGEM is a complete genetic engineering medium that can be used in lieu of MEM (or the equivalent) during chemical transfection or transduction. It allows investigators to lower the costs of their vector material and improves transfection/transduction efficiency while maintaining high cell viability and the nominal cell phenotype. The product also is very adaptable to bioprocesses where cells are genetically modified before a large cell expansion or after a cell expansion. RoosterGEM is now available in a clinically translatable cGMP format.