Article | July 6, 2021

Raw Materials In Upstream Bioproduction: Challenges And Solutions

laboratory cell splitting iStock-843420748

Developing, optimizing, and manufacturing cell culture media formulations can be a challenge and a barrier to the bioproduction process. Media formulations supporting the production of biologics, such as cell-, gene-, and protein-based therapies, consist of a large number of raw materials sourced globally from different suppliers. Media are key upstream materials that can directly affect the safety, quality, and activity of the desired product. Slight variations in the sourcing and quality of raw materials, the manufacturing process, and specifications may result in batch discrepancies, production delays, and unnecessary added costs from resource utilization and materials. Supply chains and business continuity are also key factors in ensuring a reliable raw material supply and mitigating risk from variability.

Read about the challenges related to raw materials and find your optimal solution.

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