Application Note

Quantification Of 3M™ Emphaze™ AEX Hybrid Purifier Value In mAb Manufacturing Process

By Alexei Voloshin, Himanshu Nivsarkar, 3M Separation and Purification Sciences Division

Monoclonal Antibody Purification Platform Using High-Capacity Protein A And Mixed-Mode Chromatography

This paper focuses on the 3M™ Emphaze™ AEX Hybrid Purifier and its potential effects on the cost of the manufacturing of the biopharmaceutical products. The 3M Emphaze AEX Hybrid Purifier product defines a new class of biopharmaceutical separation technologies that is able to address chromatographic separations of particles significantly larger than proteins. Integrating the 3M Emphaze AEX Hybrid Purifier in the clarification stage may simplify customers’ processes by reducing multiple types of impurities in a single process step, leading to a better process economics.

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3M Biopharmaceutical Purification