Purification Of Complex mAb Modalities: Ask The Specialists

With Jett Appel, field application scientist, Nicholas Bardol, manager, manufacturing services, and Kelly Flook, senior manager, product management, purification products

Scalability and throughput are critical considerations in complex mAb purification, as these newer modalities often lead to lower capacities, increased buffer consumption, and longer processing times. To combat these challenges, prioritizing resolution and employing specific pH ranges or non-traditional buffers is becoming more common.

In this Q&A, Thermo Fisher Scientific specialists explore the role of process optimization in improving efficiency and yield, emphasizing the importance of monitoring and utilizing quality-by-design frameworks. Learn how to navigate these complexities and improve your purification workflows. Download the full Q&A to delve deeper into expert strategies for complex mAb purification.