Newsletter | October 15, 2024

10.15.24 -- Outsourced Complex Protein Development Demands Special Considerations

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FOCUS ON OUTSOURCING

Outsourced Complex Protein Development Demands Special Considerations

Complex protein therapeutic innovators are often orchestrating the work of three, four, or more outsourced manufacturing partners at once. What goes into their selection criteria? Experts from ADC and fusion protein sponsors weigh in, with bonus commentary from a CDMO process development specialist.

A Feeder-Free Platform For Generating Mature Natural Killer Cells

NK cells represent a promising avenue for immunotherapy. Examine the advantages of NK cells in cellular immunotherapy and the importance of developing efficient activation and expansion platforms.

The High Cost Of Going Cheap

Developers often aim to cut expenses during development. Discover the long-term outcomes of cost-effective measures like using RUO leukopaks compared to investing in high-quality GMP-grade vectors.

Leveraging The Immunological Diversity Of The Pentamice Platform For Covid-19 Antibody Discovery

Consider this alternative immunization approach — the PentaMice platform, a collection of five wildtype mouse strains bred in-house for increased MHC class II diversity — and how we're leveraging it for COVID-19 antibody discovery.

A Proven AAV Platform To Drive Down Program Costs And Maximize Speed

To ensure that your adeno-associated virus (AAV) therapy reaches patients as soon as possible, begin your relationship with an experienced AAV manufacturer early in the development journey.

Realizing A New Approach To Allogeneic Cell Therapy Process Development

Increased investment in allogeneic therapies and process-level advancements to achieve commercial scale are paving the way for streamlined, standardized cell therapy development and manufacturing.

3 Key Trends Shaping The CDMO Industry

It is essential for biopharma companies to stay up to date on the future of CDMOs. Read about three key trends that are helping shape the CDMO industry.

Nanoparticle Engineering Addresses The Challenge Of Poor Aqueous Solubility

As pharma companies aim to overcome development obstacles, it is important to incorporate GMP expertise alongside novel technologies that can enhance the properties of APIs and dosage forms.

Current And Emerging Technologies To Optimize mRNA Manufacturing

Explore the benefits of using mRNA for vaccines and therapeutics, and learn how to address technical, intellectual property, and cost considerations when considering commercial production.

Considerations For Complex Formulations: How To Simplify Your Outsourcing

Experts share the necessary development and manufacturing considerations for a smooth tech transfer, exploring these challenges in depth, and discuss the questions you should be asking your manufacturer.

Leveraging Autoinjector Innovation To De-Risk Biosimilar Development

Discover how a biopharmaceutical company can de-risk the launch process by choosing a suitable autoinjector technology and partner.

PEG In LNP Formulations: Addressing Challenges And Seeking Solutions

Polyethylene glycol and similar variants have driven innovative research for therapies. However, the continued use of PEG poses significant drawbacks.

Set Your Cell And Gene Therapy Program Up For Success From Day One

Partner with a specialized CDMO early in your CGT development to ensure a streamlined path from discovery to successful commercialization, avoiding costly pitfalls and delays.

Overcoming 3 Key Challenges Facing Life Science Contract Manufacturers

Explore the key challenges faced by CMOs and CDMOs in the life sciences industry and how digital transformation can help overcome them.

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Webinar: Introducing Two New Highly Effective ADC Payloads For Cancer Therapeutics

Despite increasing interest in ADC drug development, access to safe and effective therapeutic agents (also known as payloads) and linkers is limited. Join us November 6th to learn more about Samsung Biologics’ two novel ADC payloads that demonstrate best-in-class efficacy and safety profiles upon extensive characterizations in vitro and in vivo.

OUTSOURCING SOLUTIONS

Microbial Expertise - Boehringer Ingelheim Biopharmaceuticals GmbH

Cytovance Capacity Update July 2024: Large Molecule Development - Cytovance Biologics

Developability For Complex Biologics And Bioconjugates - Abzena

ATON Bio Capacity Update July 2024: Large Molecule Development - Aton Biotech

Alcami Capacity Update May 2024: Fill/Finish - Alcami

Seamless, End-To-End Cell & Gene Therapy CDMO - GC Cell

Upstream 1 & 2 3D Facility Tour - Scorpius BioManufacturing

AAV cGMP Manufacturing Located In San Sebastian, Spain - Viralgen

Cell Line Development - EirGenix Inc.

Our Biotech Success - Pionyr - Lonza

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