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When developing a CDC assay for mAb characterization or QC testing, it's critical to select a target cell line that expresses the mAb ligand and consider CRP expression on the cell surface.
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Colloidal stability is one of the most important properties to control due to the propensity for biopharmaceuticals to aggregate and the subsequent potential to severely affect the drug's efficacy and patient safety.
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Gain a thorough understanding of the Fc region of your antibody product and how to use a risk-based approach to strategically test its functionality, optimize safety, efficacy, and development.
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Glycosylation, a prevalent modification of mAbs, significantly impacts their function. Delve into various techniques for analyzing released glycans and their relative efficacy in HILIC-FLR-MS.
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