11.11.26 -- On Demand: Tackle Aggregation, Product-Like Impurity Challenges And Scale-up

mAb aggregation can emerge at multiple points in downstream processing, affecting product quality, process yield, and manufacturing consistency. Explore key mechanisms driving mAb aggregation and practical strategies to control aggregates during chromatography and ultrafiltration/diafiltration (UF/DF) process development.

Acid-induced aggregation can create significant challenges during antibody purification, particularly for pH-sensitive monoclonal antibodies. Watch the webinar to learn how to avoid acid-induced aggregation in pH sensitive antibodies with MabSelect™ mild elution protein A resin.

Robust chromatography processes start with deeper process understanding. In this on-demand webinar, find out how DoE, mechanistic modeling, and AI can support more efficient development and help scientists make better-informed decisions.

Gain insight into how advanced analytics and chromatography strategies can improve process understanding, guide separation decisions, and reduce scale-up uncertainty as downstream purification workflows adapt to the growing complexity of emerging modalities.

Bispecific antibodies (bsAbs) have gained increasing interest in recent years because they can bind two antigens, offering unique modes of action compared to monoclonal antibodies. Discover an efficient downstream purification process for a cancer immunotherapy bispecific antibody (bsAb).