Newsletter | September 4, 2024

09.04.24 -- NIST, IBBR Researchers Explore Excipient-Influenced mAb Dynamics At Atomic Level

SPONSOR

Designing a Plasmid DNA Downstream Purification Process

Discover in our technical article the Downstream Purification in the Plasmid DNA (pDNA) Manufacturing Process. Plasmid DNA (pDNA) is an essential component of, and key technology for production of viral vector, mRNA, and vaccine therapies. The far-reaching potential of novel therapeutic modalities and vaccines that rely on pDNA is driving increased demand and the need for improved production strategies – Read Now!

FOCUS ON DOWNSTREAM MANUFACTURING

NIST, IBBR Researchers Explore Excipient-Influenced mAb Dynamics At Atomic Level

Nuclear magnetic resonance spectroscopy is powerful technique used to investigate the structure and dynamics of the drug substance in various drug formulations.

High-Concentration Drug Manufacturing Challenges And Opportunities

The demand for high-concentration/subcutaneous drugs is on the rise. Explore opportunities for enhancing your biotech drug production platform.

Building A Fully Single-Use Process With Protein A Membrane Devices

Explore results from a study demonstrating the capability of an intensified, single-use downstream process for a fed-batch cell culture harvest producing a representative mAb at an industrial scale.

The Oligonucleotide Purification & Concentration Checklist

As the demand for oligonucleotides (oligos) increases in research, therapeutics, and drug development, so does the need for advanced technologies to enhance oligo manufacturing workflows. 

Overcoming Bispecific Antibody Purification Challenges

Enhance the quality and safety of your BsAb therapeutics with a highly efficient with the right chromatography hydroxyapatite media.

Reducing Risk In mRNA Therapeutic Development

Advancements in purification, delivery mechanisms, and stability during storage and transport will enable the future of mRNA-based therapies.

SPONSOR

Webinar: Enabling Continuous Processing with Inline Buffer Formulation Systems

Join us on September 18th as we address obstacles faced during the transition to continuous processing, such as integration, real-time monitoring, and regulatory compliance. Learn practical solutions and technological advancements that can mitigate these issues, ensuring a smooth and effective implementation. We will highlight how inline buffer formulation supports seamless continuous production and how to leverage this technology to optimize your biopharmaceutical manufacturing processes.

DOWNSTREAM MANUFACTURING SOLUTIONS

Chromatography And Purification Solutions - Thermo Fisher Scientific Bioproduction

Affinity Chromatography Resin For Purifying Recombinant Proteins - Cytiva

Valved Quick Connect Couplings - Nordson MEDICAL

SPONSOR

Webinar: Cost-Effective Vaccine Manufacturing: The Role of Peptones in Enhancing Efficiency

This webinar delves into the strategic use of peptones within vaccine bioprocessing to optimize vaccine yield and quality. We will examine how the implementation of peptones in Vero and HEK cell lines can significantly reduce serum usage and enhance productivity, leading to substantial cost savings. We’ll also address the challenge of peptone variability, offering insights into how to manage consistency in your bioprocessing workflow.

Connect With Bioprocess Online: