Microcalorimetry: ITC & DSC

Isothermal titration calorimetry (ITC) and differential scanning calorimetry (DSC) are powerful analytical techniques for in-depth characterization of molecular binding events and structural stability. Thermodynamic binding signatures not only reveal the strength of a binding event, but the specific or nonspecific driving forces involved. Structural stability profiles from DSC reveal strengths and weaknesses in higher order structure and define the behavior of individual domains and their interactions. Discover three solutions that provide the performance, reliability, and ease-of-use required for the most demanding applications in drug discovery, protein-protein interactions, structure-function characterization, and more.