3M™ Polisher ST Beta Testing Series
By Atiya Hasan, Consulting Analyst, Healthcare & Life Sciences, Frost & Sullivan and Christi Bird, Consulting Director, Healthcare & Life Sciences, Frost & Sullivan
Manufacturing biopharmaceuticals at a commercial scale is a costly, complex, and lengthy process due to their unique properties and the variations of monoclonal antibodies (mAbs). Despite this, biopharmaceutical companies continually face pressures to commercialize and manufacture therapies faster and at lower costs. Consequently, technology developers like 3M™ are heeding their demands and developing innovative new technologies to improve the tedious and expensive biologics manufacturing workflow. As part of their process intensification strategies, biopharmaceutical companies and CDMOs are turning to innovations like single-use technologies that condense process steps, drive efficiency, and reduce the total cost of ownership. One such technology launched by 3M™ is their 3M™ Polisher ST—a single-use AEX chromatography device that uses a guanidinium-functionalized polyamide membrane protected by a Q-functionalized non-woven material. 3M™ Polisher ST replaces the traditional resin-based columns in the biopharmaceutical manufacturing process while simplifying the workflow. The ST stands for its functional membrane's salt tolerance capability, which allows it to function at a wide range of conductivity.
During this Frost & Sullivan Virtual Think Tank (VTT) Early Access series, the compelling feedback from the respondents made it evident that adopting the 3M™ Polisher ST in commercial manufacturing will largely overcome and eliminate these challenges. Ultimately, adoption of 3M™ Polisher ST allows for higher purity earlier on in the process train, simplifies the very complex biomanufacturing process by eliminating steps, and creates an overall robust manufacturing package that can be applied across a range of process conditions.
Get unlimited access to:
Enter your credentials below to log in. Not yet a member of Bioprocess Online? Subscribe today.