Key Considerations To Developing A Disposable Grade-A Aseptic Fill/Finish Isolation System

By Martyn Ryder, SOLO Containment, an ILC Dover LP Company

Isolation of aseptic processes is not a new technology. Rigid stainless-steel isolators have been available for decades and have been a very successful application within the industry. Flexible Film isolation has been used in aseptic processing since the 1970’s but these systems tended to be a composite of stainless-steel chambers and airflow modules with a flexible film user interface. (Hybrid: rigid/flexible). In this paper, we are going to investigate how Solo Containment (Solo) developed a fully disposable aseptic isolation system.