ABOUT US

ILC Dover, an Ingersoll Rand business, is a global leader in the design and manufacture of advanced single-use systems and flexible containment solutions for the biopharmaceutical and pharmaceutical industries. With more than 25 years of experience in single-use powder and liquid handling, we help manufacturers solve complex bioprocessing challenges while supporting safe, efficient, and scalable operations from early development through commercial production. 

Our solutions are engineered to protect people, products, and processes, enabling the safe handling of highly potent compounds, reducing contamination risk, and maintaining compliance in highly regulated environments. By integrating flexible containment technologies into modern manufacturing workflows, we help streamline operations, accelerate time-to-market, and improve overall process performance. 

ILC Dover’s biopharmaceutical portfolio includes flexible isolators, single-use containment systems, and aseptic processing solutions that support both upstream and downstream manufacturing. Designed and manufactured in ISO Class 7 cleanroom environments, our systems enable sterile, closed processing while reducing cleaning validation requirements and operational complexity. 

Biopharma Powder Handling Expertise

At the core of our offering is deep expertise in powder handling, one of the most critical and challenging areas in modern bioprocessing. Our technologies are designed to ensure precise, contained, and efficient transfer and mixing of media, buffers, and high-value materials.

•    EZ BioPac® – A purpose-built, single-use powder transfer system that accelerates media and buffer preparation while minimizing residuals, contamination risk, and cleanup requirements. 
•    JetVent™ – A controlled containment and ventilation system that maintains precise pressure environments to protect operators and ensure safe handling of potent compounds. 
•    JetMixer™ – A high-performance mixing system that enables rapid powder-to-liquid integration without shear, preserving product integrity and ensuring homogeneous results. 

Together, these technologies enable reliable powder handling workflows that improve productivity, enhance containment, and support consistent product quality across biopharma manufacturing operations.

PRODUCTS

Ensure unmatched purity across your process lines. Discover how cGMP-manufactured WFI quality water supports critical formulation, buffer prep, and cleaning workflows.

Maintain low nanogram containment thresholds during toxic linker compounding. Implement a disposable negative pressure isolation assembly with integrated double-stage exhaust filters.

Maintain a Grade-A environment for sterile fill-finish with a dual-pressure aseptic isolator. Accelerate campaign turnarounds using integrated vaporized hydrogen peroxide.

Secure big-bag transfers with solid-machined stainless steel clamping mechanisms. Ensure dust-free, airtight connections for charging and discharging bulk process materials.

Overcome powder flow and shearing challenges with a single-use fluid mixing system. Harness the Venturi effect to achieve fast, homogeneous dissolution for media and buffer preparation.

Establish safe barrier protection in minutes with a portable benchtop isolator. Secure containment for hazardous materials or inert gas processing across flexible laboratory scales.

Enhance laboratory safety with a portable, battery-operated negative pressure benchtop isolator featuring integrated HEPA filtration for immediate operator protection.

Secure your bulk powder transfer processes without sacrificing efficiency. Learn how robust, zipper-style single-use closures optimize product recovery and maintain strict containment.

Optimize material flow and contamination control in cleanroom environments. Learn how integrated containment and transport systems streamline operations and support structured 6S workflows safely.

Learn about wide-opening single-use powder transfer bags that can cut fill times by 71% and discharge times by 18% compared to traditional narrow-neck designs.

Learn how a modular selection approach to building a powered air-purifying respirator system helps deliver compliant, comfortable respiratory protection without over-specifying or under-protecting.

Learn how single-use isolator technology, purpose-built for ADC manufacturing, eliminates cleaning protocols and delivers containment performance below 10ng/M³.

Discover the advantage of platinum-cured silicone tubing, along with what quality tubing looks like in action and how it can streamline and secure your biomanufacturing processes.

The EZ BioPacZip is the latest evolution in the tried-and-true EZ BioPac® line. Combining upper and lower integrated assemblies that zip together to form a solid barrier, ILC Dover’s EZ BioPacZip is the ultimate solution for transferring dry powders for media and buffer preparation during drug development and manufacturing. Its fully closed-loop design eliminates the risk of cross-contamination and operator exposure while facilitating meticulous weight adjustments to meet precise target weights in a contained and controlled format.

The efficient mixing of powders into liquids is a crucial step in profitable biopharmaceutical manufacturing. For operations where low shear and high product integrity are required, no other technology performs as well as the JetMixer™ System from ILC Dover.

Have protection on your side with the only NIOSH approved Air-Purifying Escape Respirator with a powered ventilation system.

Explore a variety of PAPR hoods and headcovers along with their individual components such as filtration cartridges, power supplies, air delivery systems, and waist belts.

Learn about a system of single-use containers and accessories designed for handling pharmaceutical intermediate and excipient powders with moderate potency.

Learn about a state-of-the-art powered air purifying respirator through images and descriptions of what is provided in each kit.

Check out the features and benefits of the E-Crimp Tool, as well as details on the parts and what the CrimpLoc Kit includes.

Learn about flexible containment solutions that are eliminating problems associated with traditional metal and glass systems for powder handling in the pharmaceutical industry.

Check out an integrated solution for materials supply and packaging options provided by an industry-leading supplier of powder containment and transfer solutions.

Explore which options meet your needs for diverse applications by learning the benefits of cGMP raw material and their standard packaging sizes.

Learn about a custom chemical bulk packaging service that offers high-purity raw materials in precise amounts in a variety of ready-to-use configurations for cGMP manufacturers.

GuardianPac is ILC Dover’s engineered flexible intermediate bulk container system for handling non-hazardous powders used in pharmaceutical processes. View the technical specifications of the GuardianPac and it's key features.

Explore Single-Use Fluid Transfer Assemblies that can streamline your development and manufacturing by providing a high-quality, rapid, and disposable sterile fluid transfer solution.

High-purity water used for the preparation of cell culture media, buffers, and aqueous reagents.

Explore Water for Injection Quality Water produced in a cGMP-compliant USA facility and meets monographs for USP, PhEur, and JP.

ILC Dover is 100% focused on containing your process to get your product to market fast, safe, and pure. Our single-use containment solutions leverage our patented and industry-leading ArmorFlex® films to deliver extreme durability for a lower cost.

Our JetBreaker powder delumping system allows for the addition of difficult to mix powders that have large clumps to keep your process moving and allow you to dissolve powder more rapidly.

The ArmorFlex® Powder Mixer offers an array of advantages over competitive systems like the Tri-blender.

The efficient mixing of media and buffer powders into liquids is a crucial step in profitable pharmaceutical and biopharmaceutical manufacturing. For operations where low shear and high product integrity are required, no other technology performs as well as the patented venturi system used by the ILC Dover ArmorFlex® Powder Mixer.

Handling today’s higher-potency active pharmaceutical ingredients (HPAPIs) presents ever-increasing regulatory concerns — especially within manufacturing-area isolators and lab areas, and for flexible GMP chambers where airflow, temperature, humidity and pressure differentials exist from room to room.

The JetVent™ system’s precise fan speed delivers accurately controlled negative air pressure to ensure proper flow into flexible-wall isolators, while reducing the risk of worker exposure.

Dust-free bulk powder transfer from cardboard boxes, sacks or drums by means of a feed hopper with weighing frame. Positive raw material identification and registration by means of barcode scanners.

Eclipsing the traditional FIBC, the G2Pac is smart engineered to address the issues that arise from uncontrolled processes, including compromised facility cleanliness, cross contamination risks, and employee exposure to unnecessary hazards.

ILC has adapted the DoverPac® Flexible Containment Technologies to include enclosures for almost any process. Use of the ArmorFlex® film and integral gloves and sleeves will support operations from filter dryer discharge and heel removal to tray dryer loading and unloading.

The DoverPac® SF replaces the rigid polybottle for split butterfly valve powder transfer applications.

DoverPac® Continuous Liner is used for offloading powders from vessels. The DoverPac® Continuous Liner System also provides the advantage of replacing follow-on packs without breaking powder containment for continuous production.

CONTACT INFORMATION

ILC Dover, An Ingersoll Rand Business

One Moonwalker Road

Frederica, DE 19946

UNITED STATES

Phone: 1-302-335-3911 ext. 1506

Contact: ilcdover.com/en/company/locations/

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