Interview: Trends With Single-Use Bottles In Bioprocessing

Despite the widespread adoption of single-use bags, sterile bottles continue to hold a significant place in biopharmaceutical manufacturing. In an interview, Khalil Essani, Product Line Manager for Sterile Consumables at Single Use Support, sheds light on the reasons for this continued relevance. Essani explains that bottles are commonly used for more robust products, such as media, buffers, and DNA in smaller volumes. He notes that the continued use of bottles is often due to historical factors, where processes were initially optimized for their use and have since remained satisfactory.

The discussion also explores the potential for a "revival" of bottles, particularly if challenges related to closure integrity can be overcome and they are integrated into closed systems, which is a key recommendation in the EU's Annex 1 regulation. The interview also touches on other trends, such as the growing importance of sustainable bottle materials. Read the full interview to learn more about the role of sterile bottles in modern bioprocessing.