07.13.26 -- Integrated Strategies For Simplifying CHO Bioprocessing

Choosing licensed vs. unlicensed cell lines impacts development speed, cost, flexibility, and long‑term control, making early strategic evaluation key to efficient biologics development.

Parallel single-use bioreactor setups enable faster optimization, improved reproducibility, and smoother transition from development to production—supporting more efficient cell therapy workflows.

Explore temperature effects on product titer, automated cell culture development workflow, maximizing product life-cycle efficiency with the right DOE strategy, and effective data management.

Discover how controlled bioreactor environments enable optimization of critical process parameters and support robust, scalable AAV production from development through manufacturing.

Growing demand is driving interest in perfusion culture as a complementary manufacturing strategy that enables continuous nutrient control and higher productivity when paired with fed-batch processes.

Learn about a high-throughput screening method that successfully optimized cell culture media, leading to a greater than 3-fold improvement in viral genome titer for AAV2 production.

Discover how a microbial expression platform enabled high-titer production of disulfide-rich bovine knob domain antibodies with confirmed SARS-CoV-2 spike protein binding activity at 19 nM IC50.

Examine how adding Iron and B12 to fungal fermentation media increases nutritional content and impacts the biomass's texture and flavor profile, optimizing production for novel food applications.

See how Tangential Flow Depth Filtration (TFDF) enhances viral vector production, streamlining the clarification process and increasing efficiency and yield for LV and AAV manufacturing.

Gain insight into the process of transfection and why it is crucial for studying gene function and has applications in various fields, including drug development and gene therapy.