Improve Your Protein Degrader Design With New Ways To Discover E3 Ligase Ligands

Protein degradation, driven by PROTACs and molecular glues, is revolutionizing drug discovery, particularly for challenging targets. A key hurdle remains: fully mapping E3 ligases and their ligands.

This webinar presents an innovative MST-based competition assay to expand our understanding of E3 ligase ligands, specifically for cereblon (CRBN). This approach can be adapted to characterize ligands for other E3 ligases, informing the design of next-generation degraders.

If you're working on:

• Targeted protein degradation (PROTACs, molecular glues, BiDACs, MonoDACs)
• Induced proximity-based drugs for undruggable targets

This webinar provides valuable insights to stay ahead in this rapidly evolving field.