The Thermo Scientific™ HyPerforma™ Single-Use Bioreactor (S.U.B.) is one of the most widely used S.U.B.s designed for mammalian cell culture. We first launched the HyPerforma S.U.B. in 2006 and updated its design in 2013, while maintaining its robust, top-down, stirred-tank mixing system. The HyPerforma S.U.B. has been widely adopted in process development (PD) and clinical trials, as well as in bioproduction of cGMP cell culture. The new Thermo Scientific™HyPerforma™ DynaDrive™ S.U.B. is the latest advancement based on our proven innovation, which offers better performance and accommodates larger volumes.