5 Formulation Changes You Can Evaluate With Dynamic Light Scattering To Increase Your Biologics Candidates' Success

The formulation of a biologic candidate is key to protecting its overall stability and functional activity throughout the entire pipeline, from discovery to production. To optimize a candidate for the market, it's then necessary to make some formulation changes. Among other parameters, formulation scientists commonly use particle size and dispersity in solution to determine the colloidal stability of their candidates. This data is obtained from dynamic light scattering, or DLS experiments.

Read along to review the typical changes a biologic undergoes during formulation screening and how they affect the DLS read-out.