Newsletter | October 21, 2026

10.21.26 -- Finding Balance Between Viral Vector Purity And Quantity

FOCUS ON DOWNSTREAM MANUFACTURING

Finding Balance Between Viral Vector Purity And Quantity

In this segment from the Bioprocess Online Live event, "Downstream Decisions To Maximize Viral Vector Yields And Reduce COGs," panelists Hung Trinh, Ph.D., and Nathalie Clément, Ph.D., discuss the tradeoff between yield recovery and product quality. They agree that a focus on product purity is a necessity, but this purity comes at the cost of reduced yields downstream.

 

 

Conventional Cooling Vs. Controlled Ice Nucleation On Primary Drying Time

Discover how controlled ice nucleation shortens lyophilization cycles, supports higher drying temperatures, and reduces complexity for amorphous and mixed formulations without sacrificing quality.

 

Enhancing Process Development With Viral Clearance

Streamline mAb purification with confidence. Learn practical considerations for developing processes with advanced mixed-mode chromatography, ensuring superior impurity and viral clearance.

 

Future-Proof Workflows With Preventive Maintenance

Preventive maintenance helps teams reduce downtime, control costs, and stay inspection‑ready. Find out how proactive, data‑driven maintenance strategies can protect equipment performance.

 

What Is Drug Antibody Ratio (DAR) And How It Relates To Biotherapeutics?

DAR is a key quality attribute that shapes ADC potency, safety, stability, and developability. See why accurate measurement and control are essential as ADC pipelines expand and expectations rise.

 

Optimize Time, Space and Cost With Inline Buffer Formulation And System

Explore how integrating inline buffer formulation with chromatography reduces buffer waste by 50% and delivers a 710% ROI, transforming downstream efficiency and sustainability.

 

Detect Low-Abundance GLP-1 Impurities With Greater Sensitivity

Low-level impurities can be difficult to resolve using conventional approaches. Examine how a Charged Surface 2.3 µm superficially porous Phenyl-Hexyl column enhances reversed-phase LC-MS analysis.

 

Bioprocessing Applications Laboratories

Bioprocessing applications labs help enable data-driven process optimization. Delve into how integrated expertise and application testing can help reduce bottlenecks and de-risk steps.

DOWNSTREAM MANUFACTURING SOLUTIONS

•

Small-Scale GMP Manufacturing With A Chromatography System - Cytiva

•

Bioprocessing Ecosystem For Downstream And Mixing - MilliporeSigma

•

AI-Driven GxP Manufacturing - Aizon

•

Swiftly Assess Protein L Impurity - Cygnus Technologies Inc.

FOCUS ON FILL-FINISH

 

Unlocking Durable Allogeneic Cell Therapy

Advances in genome engineering and immune evasion are enabling scalable, durable allogeneic cell therapies, overcoming rejection challenges and expanding potential treatments across diverse diseases.

 

Aseptic Filling By Design: Shaping The Future Of Drug Manufacturing

Modern therapies demand higher sterility assurance and flexibility. Take a look at how advanced contamination control, barrier systems, and automation strengthen quality and support faster delivery.

 

New Container Protects Bulk Frozen Biopharmaceuticals

Gain insight into a flexible freeze container that maintains package integrity after freezing at -86 °C (-123 °F) through its durable design, minimizing product loss due to package failure.

FILL-FINISH SOLUTIONS

•

Automate Your Fill/Finish Process For Precision - Terumo BCT

•

Reliable Sterile Manufacturing - Jubilant HollisterStier

Connect With Bioprocess Online: