|
|
|
| Seed Train Intensification | Achieving greater productivity in your mAb process starts with the seed train. Seed train intensification supports improved efficiency, increased flexibility, and reduced risk in mAb manufacturing. Options to accelerate cell expansion and achieve higher cell densities include perfusion operations and high cell density cryopreservation methods. Interested in exploring the advantages of intensification? Request a demo of the Cellicon® Cell Retention Solution, or get a free sample of our Mobius® HCDC Assembly today! |
|
|
FOCUS ON UPSTREAM MANUFACTURING |
|
|
|
A conversation with Tanishka Kumar | Electroporation creates temporary holes in cell membranes for genetic material to slip through. The technique offers some key advantages to viral transduction. | |
|
|
| Tackling Allogeneic Immunotherapy's Scale-Up Bottleneck | Application Note | PBS Biotech, Inc. | New bioreactor technology provides an optimal environment for shear-sensitive cells, addressing key scale-up challenges for allogeneic therapies from research to commercial production. |
|
|
|
| Complex Antibody Expression - Challenge Accepted | Webinar | Sartorius | Explore how tailored cell line development strategies are enabling high-yield production of complex biologics and reveal how automation and data modeling drive success in CHO cell line development. |
|
|
| Viral Vector Manufacturing Using Tangential Flow Depth Filtration | Poster | By Riaj Mahamud, Ly Truong, Marlon Tannous, Westley Blacklock, et al., Repligen | Address the rising gene therapy demands with an innovative perfusion strategy that significantly boosts cell density and viral vector yields to pave the way for scalable, efficient manufacturing. |
|
|
|
| Quantifying Cell Response With Duplex RT-qPCR | Webinar | Catalent | Discover a new potency bioassay using RT-qPCR to assess relative transcription activity, and learn more about the advantages and limitations of transcriptional assays versus reporter gene assays. |
|
|
|
|
| Streamlining Cell Line Development For Antibodies | Article | Danaher Life Sciences | Streamline your antibody production with a robust Cell Line Development strategy. Discover how automation, analytics, and digital tools accelerate development from clone selection to commercialization. |
|
|
| Advanced mAb Process Intensification Strategies | Article | Thermo Fisher Scientific | Advancements in perfusion media, high-density cell banking, and downstream intensification are streamlining biologics manufacturing for greater efficiency and cost-effectiveness. |
|
|
|
|
| Webinar: From Lab To Commercialization: Simplifying Bioprocess Scale-Up | Discover how Thermo Fisher Scientific’s DynaDrive™ Single-Use Bioreactors enable seamless scale-up from 1L to 5,000L. This webinar explores the cuboid design’s mixing advantages, real-world case studies, and strategies to overcome process development challenges. Learn how innovative geometry boosts flexibility, sustainability, and productivity for fed-batch and perfusion applications in process development, MSAT, and manufacturing. Click here to learn more. |
|
|
UPSTREAM MANUFACTURING SOLUTIONS |
|
|
|
|
|
|
|
|
|
| Connect With Bioprocess Online: |
|
|
|
