Newsletter | February 17, 2025

02.17.25 -- Easing Autologous Cell Collection, Automating Manufacturing

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Following its popular inaugural 2024 Bio-Expo Live, Bioprocess Online brings you the next opportunity to advance your drug development agenda. Over just a small portion of your week and from the comfort of your computer, discover the latest solutions in upstream and downstream bioprocessing as well as bioprocess quality, data, and analytics. 15-minute presentations from leading suppliers will give you just the right insight to make your next best move in drug development. Register here.

FOCUS ON UPSTREAM MANUFACTURING

Easing Autologous Cell Collection, Automating Manufacturing

To circumvent the challenges of leukapheresis, CellProthera developed a novel method for collecting therapeutic stem cells from whole blood. CSO Ibon Garitaonandia, Ph.D., discusses the company's mission to streamline manufacturing.

Utilizing Fed-Batch Intensification To Increase Titer

Learn how the advanced principles of process intensification can be applied to process and equipment design, increasing facility throughput, and ultimately offering a wide range of benefits to customers.

Exploring Perfusion Technology For Process Intensification

Perfusion cell culture technology supports high cell densities and product yields for viral vaccine manufacturing, offering a reliable way to produce high-quality cells at a commercial scale.

Determining The Power Numbers For A Single-Use Mixing System

In designing a mixing process for scale-up, the power number is a critical parameter. Explore the determined power numbers for a single-use mixer at various mixing speeds and fill levels.

A Chemically Defined Medium Supports Cross-Platform T-Cell Expansion

T-cell manufacturing processes utilizing a novel cell culture medium represent an important step forward in making adoptive T-cell therapy more consistent and scalable to better serve patients.

The Benefits Of Coatings For Bioproduction: Stem Cells And Coatings

Coatings for cell culture surfaces are an important factor in maintaining the health and pluripotent properties of stem cells.

Accelerate Antibody Development And Production

This electroporation platform accelerates therapeutic antibody development with scalable, high-efficiency transfection, enabling rapid transient protein expression, and IND-enabling studies in just weeks.

Considerations For Successful Upstream Manufacturing Process Scale-Up

A CDMO’s ability to scale seamlessly between bioreactor sizes is critical when adopting a client’s manufacturing process.

What Every Scientist Should Know About Their Orbital Throw

Master orbital throw by understanding its impact on aeration, mixing, and growth. Explore recommendations for various applications and the benefits of adjustable throw incubator shakers.

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Webinar: Bioprocess Optimization – Leveraging Functional DOE with Time-based Insights

While traditional Design of Experiments (DOE) methods help identify critical quality attributes and process parameters, they often focus on single-value outcomes, which narrowed focus overlooks the dynamic, time-dependent nature of bioprocesses. Join Samsung as they explore how functional DOE addresses this gap by leveraging time-based data to predict the evolution of key process parameters and uncover complex interactions, providing deeper insights for optimizing bioprocesses. Learn more.

UPSTREAM MANUFACTURING SOLUTIONS

Cell And Media Kits - RoosterBio

Integrated Technologies For Biologics Developability Assessment - NanoTemper Technologies, Inc.

High-Viability Cell Processing, Simplified - CARR Biosystems

Pore Morphology And Pre-Filters - Entegris, Inc.

SUREtechnology Platform - KBI Biopharma

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